Magnesium Citrate Supplementation Impact on Blood Sugar, Blood Pressure and Gene Expression in Type II Diabetes Patients

This study focuses on understanding the effects of magnesium citrate supplementation in individuals with type 2 diabetes. The research involves 50 participants aged between 20 and 80 years, all of whom have type 2 diabetes (indicated by HbA1c levels above 6%). The primary goal is to explore how a 12-week course of 400 mg magnesium citrate daily might impact blood sugar levels, blood pressure, and the expression of genes sensitive to magnesium. This research is important as it could potentially uncover new ways to manage type 2 diabetes, improving the quality of life for those affected. During the study, participants will take the magnesium citrate supplement daily. The study's progress will be tracked through blood tests at the beginning, midpoint (6 weeks), and end (12 weeks). These tests will measure relevant parameters like glucose, HbA1c, and HOMA-IR, as well as the expression of magnesium-sensitive genes. Additionally, blood pressure will be monitored and a standardized questionnaire (SF-36) will be used to assess each participant's general health condition. The study aims to provide valuable insights into the potential benefits and risks associated with magnesium citrate supplementation for individuals with type 2 diabetes.