Completed

Prevalence and Clinical Characteristics of Obesity Hypoventilation Syndrome in Critically Ill Obese Patients

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Study Aim

This study aims to observe and determine the prevalence of obesity hypoventilation syndrome among critically ill Asian patients with a Body Mass Index (BMI) of 30 kg/m² or higher in intensive care units.

What is being collected

Data Collection

Collected from today forward - Prospective
Who is being recruted

Apnea+14

+ Hypoventilation

+ Nervous System Diseases

From 20 to 80 Years
+11 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Cohort

Tracking disease incidence in order to identify risk factors and understand disease progression over time.
Observational
Study Start: October 2014
See protocol details

Summary

Principal SponsorNational Taiwan University Hospital
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: October 29, 2014

Actual date on which the first participant was enrolled.

This study focuses on a health condition called Obesity Hypoventilation Syndrome (OHS), which affects individuals who are obese, specifically those with a Body Mass Index (BMI) of 30 kg/m2 or higher. The research is conducted in medical intensive care units, targeting adult patients who have recently been admitted and diagnosed with OHS. The main goal is to understand how common this condition is among critically ill patients and to identify factors that might predict its occurrence, thereby improving care and addressing current challenges in managing OHS. The study is observational in nature, meaning participants will undergo routine medical care while their health is closely monitored. Researchers will screen for OHS among obese patients in the intensive care unit, observing its prevalence in this specific population. The primary outcome measured is the prevalence of OHS among Asian critically ill patients. This will be achieved by screening for obesity (BMI>=30kg/m^2) in critical care units, providing valuable insights into the condition's prevalence in the Asian population.

Official TitlePrevalence Rate, and Clinical Characteristics of Obesity Hypoventilation Syndrome Via Screening Patients Admitted to Medical Intensive Care Units
NCT02934581
Principal SponsorNational Taiwan University Hospital
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

52 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Cohort

These studies follow a group of individuals with common characteristics (such as a condition or birth year) over a specific period to study health outcomes or exposures.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 20 to 80 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

ApneaHypoventilationNervous System DiseasesNutrition DisordersNutritional and Metabolic DiseasesObesityObesity Hypoventilation SyndromeRespiration DisordersRespiratory InsufficiencyRespiratory Tract DiseasesSleep Apnea SyndromesSleep Wake DisordersSleep Apnea, ObstructiveSleep Disorders, IntrinsicDyssomniasOvernutritionOverweight

Criteria

2 inclusion criteria required to participate
BMI ≥ 30 kg/m2

Suspected chronic hypercapnia as following Paco2 ≥ 45 mmHg, HCO3- ≥ 27mEq/L or base excess, BE ≥ 2 mEq/L

9 exclusion criteria prevent from participating
Malignancy with lung involvement

Autoimmune disease with lung involvement

Moderate to severe obstructive respiratory pattern via spirometry

Uncontrolled endocrine disease

Show More Criteria

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Study Objectives

Study Objectives

Primary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

National Taiwan University Hospital

Taipei, TaiwanOpen National Taiwan University Hospital in Google Maps
CompletedOne Study Center