Suspended

Catgut Embedding Therapy for Obesity in Females: Impact on BMI, Waist Circumference, and Quality of Life

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Study Aim

This study aims to evaluate the effectiveness of Catgut Embedding Therapy as a treatment for obesity in females, focusing on improvements in body mass index, body weight, hip circumference, and waist circumference.

What is being tested

Catgut embedding group

+ sham catgut embedding group

Device
Who is being recruted

From 20 to 65 Years
+2 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Treatment Study

Placebo-ControlledPhase 4
Interventional
Study Start: January 2014
See protocol details

Summary

Principal SponsorTaipei City Hospital
Last updated: January 27, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: January 1, 2014

Actual date on which the first participant was enrolled.

This clinical trial focuses on treating obesity in females. It specifically targets those aged between 16 and 65, with a body mass index of 27 or above, and a waist circumference of 80 cm or more. The study explores the therapeutic effects of catgut embedding, a technique where surgical sutures are inserted into specific points on the body. These points, located on the abdomen, have shown potential in managing obesity in previous research. The goal is to understand if this method can improve obesity and enhance the quality of life for these women. During the trial, participants are randomly divided into two groups. One group receives catgut embedding at six acupuncture points on the abdomen, once a week for six weeks. The other group undergoes a sham procedure, mimicking the real one but without actual catgut embedding. The primary outcomes measured are changes in body mass index, waist and hip circumference, and body weight. Additionally, the study evaluates the participants' quality of life using health surveys and questionnaires. Blood tests are also conducted to check lipid profiles, inflammatory markers, and hormones related to obesity. These assessments happen before the treatment begins and after it ends, to determine the effectiveness of catgut embedding in managing obesity.

Official TitleThe Therapeutic Effect of Catgut Embedding in Obesity-A Randomized, Double-blind, Placebo-controlled Clinical Trial
NCT02276235
Principal SponsorTaipei City Hospital
Last updated: January 27, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

90 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Criteria

Female

Biological sex of participants that are eligible to enroll.

From 20 to 65 Years

Range of ages for which participants are eligible to join.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Criteria

1 inclusion criteria required to participate
body mass index (BMI) ≥ 27 kg/m2 waist circumference (WC) ≥ 80 cm and willing to participate in and fill out the questionnaires for this trial.

1 exclusion criteria prevent from participating
Endocrine disease(Thyroid disease, pituitary disease, diabetes mellitus) Autoimmune disease(SLE、SSS、RA) Heart disease(Heart failure, arrhythmia etc.) Abnormal liver function(GOT>80U/L、GPT>80U/L) Abnormal kidney function(serum creatinine>2.5 mg/dL) Stroke disease in past one year Under breast feeding or pregnancy Coagulation disorder Subjects with keloid disorder Accept weight reduction treatment in last two months

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

2 intervention groups are designated in this study

50% chance of being blinded to the placebo group

Treatment Groups

Group I

Experimental
Catgut will be embedding in acupoints as below. Acupoints: Qihai (REN-6), Shuifen (REN-9), bilateral Shuidao (ST-28),bilateral Siman (K-14) ,zusanli(ST-26) Frequency: one time per week Duration: 6 weeks

Group II

Sham
The stainless-steel acupuncture needles (3.8cm long) was inserted into 23 gouge needle as plunger without chromic catgut in front of the syringe needle. All the procedure will be performed as in catgut embedding group. Acupoints: Qihai (REN-6), Shuifen (REN-9), bilateral Shuidao (ST-28),bilateral Siman (K-14) ,zusanli(ST-26) The other procedure were the same as catgut embedding group Frequency: one time per week Duration: 6 weeks

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

Branch of Chinese Medicine, Taipei City Hospital

Taipei, TaiwanOpen Branch of Chinese Medicine, Taipei City Hospital in Google Maps
SuspendedOne Study Center