Suspended

Chronic Granulomatous Disease Study in China

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What is being collected

Data Collection

Collected from today forward - Prospective
Who is being recruted

Chronic Disease+11

+ Granulomatous Disease, Chronic

+ Hematologic Diseases

+4 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Cohort

Tracking disease incidence in order to identify risk factors and understand disease progression over time.
Observational
Study Start: September 2014
See protocol details

Summary

Principal SponsorShanghai Children's Medical Center
Study Contactjing wu
Last updated: January 27, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: September 1, 2014

Actual date on which the first participant was enrolled.

CGD is a rare inherited primary immunodeficiency which is caused by the defect in one of the subunits of NADPH oxidase complex.We tend to collect and analyze Chinese CGD patients who are diagnosed in hospitals affiliated to Shanghai Jiao Tong University School of Medicine, including clinical feature, laboratory data and genetic information. we aim to find out clinical, distribution, genetic characteristic of CGD in Chinese population, etc., thus further improving the level of diagnosis and treatment for CGD.

Official TitleChronic Granulomatous Disease Study in China
NCT02231996
Principal SponsorShanghai Children's Medical Center
Study Contactjing wu
Last updated: January 27, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

50 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Cohort

These studies follow a group of individuals with common characteristics (such as a condition or birth year) over a specific period to study health outcomes or exposures.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Chronic DiseaseGranulomatous Disease, ChronicHematologic DiseasesHemic and Lymphatic DiseasesImmunologic Deficiency SyndromesImmune System DiseasesLeukocyte DisordersCongenital, Hereditary, and Neonatal Diseases and AbnormalitiesPathologic ProcessesPhagocyte Bactericidal DysfunctionPathological Conditions, Signs and SymptomsDisease AttributesGenetic Diseases, InbornGenetic Diseases, X-Linked

Criteria

3 inclusion criteria required to participate
x-linked and AR-linked Chronic Granulomatous Disease
history of life-threatening severe infections
A functional assay demonstrating abnormal NADPH oxidase function or clinical history consistent with CGD
1 exclusion criteria prevent from participating
Presence of other primary immunodeficiency syndromes that do not meet the clinical and laboratory criteria for CGD.

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Study Objectives

Study Objectives

Primary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

Shanghai children's medical center

Shanghai, ChinaOpen Shanghai children's medical center in Google Maps
SuspendedOne Study Center