Suspended
Exparel (Bupivacaine Liposome Injectable Suspension) for Distal Upper Extremity Blocks in Orthopedic Surgery
What is being tested
Exparel Forearm block
+ Bupivacaine supraclavicular block
Drug
Who is being recruted
Arm Injuries+9
+ Finger Injuries
+ Hand Injuries
Over 18 Years
+14 Eligibility Criteria
How is the trial designed
Treatment Study
Phase 4
Interventional
Study Start: February 2014
Summary
Principal SponsorJose Soberon, MD
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner
Study start date: February 1, 2014
Actual date on which the first participant was enrolled.The purpose of this study is to compare Exparel, a new, long-lasting numbing medication and a shorter-acting nerve block to a traditional single-shot nerve block in patients having hand, wrist or finger surgery.
Official TitleExparel (Bupivacaine Liposome Injectable Suspension) for Distal Upper Extremity Blocks in Orthopedic Surgery
Principal SponsorJose Soberon, MD
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.Design Details
37 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Treatment Study
These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Conditions
Criteria
Any sex
Biological sex of participants that are eligible to enroll.Over 18 Years
Range of ages for which participants are eligible to join.Healthy volunteers allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Arm InjuriesFinger InjuriesHand InjuriesNeurologic ManifestationsPainPain, PostoperativePathologic ProcessesPostoperative ComplicationsSigns and SymptomsPathological Conditions, Signs and SymptomsWounds and InjuriesWrist Injuries
Criteria
4 inclusion criteria required to participate
patients 18 years or older having hand, wrist, or finger surgery
ability to understand and provide informed consent
American Society of Anesthesiologists status I-III
presence of a responsible adult caregiver for 48-72 hours after surgery
10 exclusion criteria prevent from participating
patient refusal or inability to provide informed consent
true allergy, not sensitivity to local anesthetics, midazolam, fentanyl, hydromorphone, propofol
pregnancy
hepatic or renal failure
Show More Criteria
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.Treatment Groups
Study Objectives
2 intervention groups are designated in this study
This study does not include a placebo group
Treatment Groups
Group I
ExperimentalUnder ultrasound guidance, 3-5 milliliters (mL) Exparel will be injected around the 3 nerves of the forearm prior to surgery. 20-30 mL Mepivacaine will be used for the supraclavicular block following the forearm block.
Group II
Active ComparatorUnder ultrasound guidance, 20-30 mL 0.5% Bupivacaine will be used for the supraclavicular block.
Study Objectives
Primary Objectives
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 1 location
Suspended
SuspendedOne Study Center