Completed

Urinary Proanthocyanidin (PAC) A2 as a Biomarker of Compliance to Intake of Cranberry Products - A Pilot Study

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What is being tested

cranberry juice

Other
Who is being recruted

Treatment Adherence and Compliance+9

+ Urogenital Diseases

+ Behavior

From 20 to 40 Years
+30 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Basic Science Study

Interventional
Study Start: September 2012
See protocol details

Summary

Principal SponsorTufts University
Last updated: January 27, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: September 1, 2012

Actual date on which the first participant was enrolled.

People who frequently eat whole grains, fruits and berries, vegetables, beans and legumes, nuts, seeds, cocoa, tea, wine, and fruit or vegetable juices may have decreased risk of diseases. It is believed that some of these health benefits are due to phytochemicals present in these foods and beverages. Phytochemicals are nutrients that are naturally present in plant-based foods and beverages. Recently, cranberry containing foods and beverages are believed to prevent urinary tract infection. However, how cranberry decrease urinary tract infection is not very clear. To better understand how phytochemicals in cranberries may benefit health, we want to learn how they are absorbed and eliminated from the body. Thus, the purpose of the main study is to see whether we can measure phytochemicals from cranberries in health volunteers after they drink cranberry juice.

Official TitleUrinary Proanthocyanidin (PAC) A2 as a Biomarker of Compliance to Intake of Cranberry Products - A Pilot Study
NCT01687114
Principal SponsorTufts University
Last updated: January 27, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

5 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Basic Science Study

Basic science studies help researchers understand how the body works or how a disease develops. They don't test treatments, but they build the foundation for future therapies.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Female

Biological sex of participants that are eligible to enroll.

From 20 to 40 Years

Range of ages for which participants are eligible to join.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Treatment Adherence and ComplianceUrogenital DiseasesBehaviorFemale Urogenital Diseases and Pregnancy ComplicationsInfectionsPatient Acceptance of Health CarePatient ComplianceUrinary Tract InfectionsUrologic DiseasesHealth BehaviorFemale Urogenital DiseasesMale Urogenital Diseases

Criteria

5 inclusion criteria required to participate
generally healthy premenopausal women

aged 20-40 y

body mass index (BMI): 18.5-25 kg/m2

sexually active but not pregnant or planning to become pregnant

Show More Criteria

25 exclusion criteria prevent from participating
Infrequent (<3/wk) or excessive (>3/d) number of regular bowel movements

Use of medications known to affect lipid metabolism

History of a bilateral mastectomy

Use of medications known or suspected to influence blood pressure

Show More Criteria

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

One single intervention group is designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Experimental
27% cranberry juice

Study Objectives

Primary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

Jean Mayer USDA Human Nutrition Research Center on Aging

Boston, United StatesOpen Jean Mayer USDA Human Nutrition Research Center on Aging in Google Maps
CompletedOne Study Center