Recruiting

SCADRegistry for Spontaneous Coronary Artery Dissection (SCAD) Patients

0 criteria met from your profileSee at a glance how your profile meets each eligibility criteria.
What is being collected

Data Collection

Who is being recruted

Arterial Occlusive Diseases+11

+ Arteriosclerosis

+ Cardiovascular Diseases

Over 18 Years
+8 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Cohort

Tracking disease incidence in order to identify risk factors and understand disease progression over time.
Observational
Study Start: July 2011
See protocol details

Summary

Principal SponsorMayo Clinic
Study ContactSusan Milbrandt
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: July 1, 2011

Actual date on which the first participant was enrolled.

Spontaneous Coronary Artery Dissection (SCAD) is a condition that isn't well understood and tends to affect more women than men. It happens when two layers of the coronary arteries separate, allowing blood to flow into the space between them. This can block normal blood flow in the heart, leading to chest pain, heart attacks, and in some cases, sudden death. To better understand and prevent this potentially life-threatening event, Mayo Clinic is conducting studies on SCAD. One of these studies aims to build a database of patients with SCAD, regardless of whether they've been treated at Mayo Clinic or not. The goal is to identify patterns in SCAD occurrence, causes, and associations, which could guide future research and improve care for this condition. With the participant's consent, Mayo Clinic staff will request a copy of the original coronary angiogram, the test used to diagnose SCAD, to confirm the diagnosis and determine eligibility. If eligible, study coordinators will reach out to the participant to provide more information about the studies and request a signed informed consent document. The primary goal of this observational study is to gather data about SCAD-related risk factors, symptoms at diagnosis, treatments used, and long-term outcomes for patients.

Official TitleThe "Virtual" Multicenter Spontaneous Coronary Artery Dissection (SCAD) Registry
NCT01429727
Principal SponsorMayo Clinic
Study ContactSusan Milbrandt
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

2500 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Cohort

These studies follow a group of individuals with common characteristics (such as a condition or birth year) over a specific period to study health outcomes or exposures.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Over 18 Years

Range of ages for which participants are eligible to join.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Arterial Occlusive DiseasesArteriosclerosisCardiovascular DiseasesCoronary Artery DiseaseCoronary DiseaseHeart DiseasesInfarctionIschemiaMyocardial InfarctionNecrosisPathologic ProcessesPathological Conditions, Signs and SymptomsVascular DiseasesMyocardial Ischemia

Criteria

8 inclusion criteria required to participate
Individuals who have been cared for at Mayo Clinic with a diagnosis of SCAD

SCAD in women who are pregnant or within 12 months postpartum at the time of SCAD

SCAD in individuals who self-identify as a member of a racial or ethnic group that is currently underrepresented in the registry. This would include anyone who identifies as: Black/African American, Asian, American Indian or Alaska Native, Native Hawaiian or Other Pacific Islander, and any race with Hispanic ethnicity

SCAD in a man

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Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Study Objectives

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Recruiting

Mayo Clinic

Rochester, United StatesOpen Mayo Clinic in Google Maps
Recruiting
One Study Center