Completed
Oxyntomodulin, Mechanisms of Action in Relation to Appetite, Food Intake, Gastric Emptying and Energy Expenditure.
What is being collected
Data Collection
DNA Samples
Who is being recruted
Body Weight+5
+ Nutrition Disorders
+ Nutritional and Metabolic Diseases
From 18 to 70 Years
+13 Eligibility Criteria
How is the trial designed
Observational
Study Start: October 2010
Summary
Principal SponsorUniversity Hospital, Gentofte, Copenhagen
Last updated: January 27, 2026
Sourced from a government-validated database.Claim as a partner
Study start date: October 1, 2010
Actual date on which the first participant was enrolled.Tiny molecules (hormones) are released from the bowels and other organs to the bloodstream in response to meals in order to orchestrate the metabolism. Oxyntomodulin, GLP-1 and glucagon are all known to regulate parameters such as appetite, food intake and induce weight loss. Therefore we want to investigate mechanistic relations between the three hormones.
Official TitleOxyntomodulin, Mechanisms of Action in Relation to Appetite, Food Intake, Gastric Emptying and Energy Expenditure.
Principal SponsorUniversity Hospital, Gentofte, Copenhagen
Last updated: January 27, 2026
Sourced from a government-validated database.Claim as a partner
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.Design Details
15 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Conditions
Criteria
Male
Biological sex of participants that are eligible to enroll.From 18 to 70 Years
Range of ages for which participants are eligible to join.Healthy volunteers allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Body WeightNutrition DisordersNutritional and Metabolic DiseasesObesitySigns and SymptomsPathological Conditions, Signs and SymptomsOvernutritionOverweight
Criteria
4 inclusion criteria required to participate
Normal fasting plasma glucose
Normal glucose tolerance
Normal haemoglobin levels
Informed content
9 exclusion criteria prevent from participating
Diabetes
Pre diabetes (impaired glucose tolerance or impaired fasting glucose)
1st degree relatives with diabetes
Obesity (BMI > 30)
Show More Criteria
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.Study Objectives
Study Objectives
Primary Objectives
Secondary Objectives
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 1 location
Suspended
CompletedOne Study Center