Completed

Acupuncture for Pain Relief During Induced Labour in Nulliparae: a Randomised Controlled Study

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What is being tested

acupuncture

Procedure
Who is being recruted

Neurologic Manifestations+1

+ Pain

+ Signs and Symptoms

Over 18 Years
See all eligibility criteria
How is the trial designed

Treatment Study

Placebo-Controlled
Interventional
Study Start: August 2005
See protocol details

Summary

Principal SponsorUniversity of Oxford
Last updated: January 27, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: August 1, 2005

Actual date on which the first participant was enrolled.

This study focuses on first-time pregnant women who are having their labor induced due to a prolonged pregnancy or mild high blood pressure. The main goal is to explore the potential of acupuncture as a method for pain relief during this process. The study is important as it aims to find alternative ways to manage labor pain, which could potentially reduce the need for epidural analgesia, a common form of pain relief during childbirth that involves injecting medication into the lower back. The study involves four groups, each managed differently. One group receives manual acupuncture, another receives electro acupuncture, the third group receives sham acupuncture, and the last group receives no treatment. Manual and electro acupuncture involve the insertion of thin needles into specific points on the body, with electro acupuncture also using a mild electric current. Sham acupuncture mimics the process but without actual needle insertion. The study's primary outcome is to measure the rate of epidural analgesia administered during labor, which will help evaluate the effectiveness of acupuncture in managing labor pain.

Official TitleAcupuncture for Pain Relief During Induced Labour in Nulliparae: a Randomised Controlled Study
Principal SponsorUniversity of Oxford
Last updated: January 27, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

105 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Female

Biological sex of participants that are eligible to enroll.

Over 18 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Neurologic ManifestationsPainSigns and SymptomsPathological Conditions, Signs and Symptoms

Criteria

Inclusion Criteria: * nulliparae * having labour induced for prolonged pregnancy or mild hypertension * no previous experience of acupuncture * give written informed consent Exclusion Criteria: * all who do not meet the inclusion criteria

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

3 intervention groups are designated in this study

33.333% chance of being blinded to the placebo group

Treatment Groups

Group I

Sham
Sterile needles were inserted adjacent to the specific acupuncture sites identified for the manual and electro groups to a depth of 1-1.5mm only and insufficient to provoke an unusual sensation and left in position for a 30-60 minutes. Those randomised to 'sham-manual' received no stimulation and those randomised to 'sham-electro' were connected to the electrical stimulator but the current not activated.

Group II

Experimental
Sterile needles were inserted intramuscularly to a depth of 15-20mm until an unusual (De-Qi) sensation developed and remained inserted for 30-60 minutes and were either electronically simulated withm2 Hz pulses of 0.5 msec duration for 30 minutes sufficient to cause non-painful muscle contractions. The following bilateral acupoints on the hands and feet at Hegu (LI 4), Sanyinjiao (Sp 6) Kunlun (BL 60) and Zhiyin (BL 67)were used.

Group III

Experimental
Sterile needles were inserted intramuscularly to a depth of 15-20mm until an unusual (De-Qi) sensation developed and remained inserted for 30-60 minutes and were manually manipulated during this time. The following bilateral acupoints on the hands and feet at Hegu (LI 4), Sanyinjiao (Sp 6) Kunlun (BL 60) and Zhiyin (BL 67)were used.

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

John Radcliffe Hospital

Oxford, United KingdomOpen John Radcliffe Hospital in Google Maps
CompletedOne Study Center