Suspended

Pediatric Elective Intubation With and Without Muscle Relaxation Utilizing the Shikani Optical Stylet

0 criteria met from your profileSee at a glance how your profile meets each eligibility criteria.
What is being tested

Cisatracurium

+ Normal saline

Drug
Who is being recruted

From 6 Months to 17 Years
See all eligibility criteria
How is the trial designed

Treatment Study

Placebo-Controlled
Interventional
Study Start: January 2007
See protocol details

Summary

Principal SponsorRady Children's Hospital, San Diego
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: January 1, 2007

Actual date on which the first participant was enrolled.

The investigators' primary specific aims are to demonstrate that: 1. Pediatric patients with normal airways, undergoing elective surgical procedures, can be successfully intubated when deeply sedated, without the use of muscle relaxants using the Shikani Optical Stylet. 2. Shikani intubation of pediatric patients is equally effective in children that are deeply sedated or paralyzed as evidenced by a non-significant difference in: * Time to intubation (defined as no more than a 30 second time difference between the two groups); * Incidence of adverse events.

Official TitlePediatric Elective Intubation With and Without Muscle Relaxation Utilizing the Shikani Optical Stylet
NCT00912990
Principal SponsorRady Children's Hospital, San Diego
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

34 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 6 Months to 17 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Criteria

Inclusion Criteria: * 6 months of age to 17 years of age (not yet 18) * Male or female * English or Spanish speaking * Normal airway (Mallampati Classification ) * American Society of Anesthesiology Physical Status Classification I or II * Elective surgical procedure expected to last at least 45 minutes in length * Written informed consent/assent for participation given by the parent legal guardian and subject (if applicable) Exclusion Criteria: * \< 6 months of age, \> 17 years of age * Difficult airway (Mallampati Classification) * History of previous difficult intubation, suspected abnormal airway: \*micrognathia * facial trauma * airway tumor * epiglottitis * retropharyngeal abscess * foreign body, etc. * Scheduled for non-elective, emergent OR procedure * Parent, legal guardian, or subject is unavailable or unwilling to consent for study participation

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

2 intervention groups are designated in this study

50% chance of being blinded to the placebo group

Treatment Groups

Group I

Active Comparator
Subjects in this arm will be given Cisatracurium 0.2mg/kg IV dose one time prior to intubation.

Group II

Placebo
Normal saline volume calculated to be equal to the volume of cisatracurium 0.2mg/kg

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

Rady Children's Hospital

San Diego, United StatesOpen Rady Children's Hospital in Google Maps
SuspendedOne Study Center