Completed

Basal Cell Carcinoma Recurrence

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What is being collected

Data Collection

Collected from today forward - Prospective
Who is being recruted

Carcinoma+7

+ Carcinoma, Basal Cell

+ Neoplasms

Over 18 Years
+9 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Cohort

Tracking disease incidence in order to identify risk factors and understand disease progression over time.
Observational
Study Start: May 2008
See protocol details

Summary

Principal SponsorNorthwestern University
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: May 1, 2008

Actual date on which the first participant was enrolled.

Basal cell carcinoma (BCC) is the most common nonmelanoma skin cancer in the United States, affecting nearly one million of all Americans. While BCC is rarely mortal, it has significant associated physical, psychological, and monetary costs to patients such as disfigurement and sensory loss. Individuals who have been diagnosed with at least one BCC lesion are likely to be diagnosed with more in the future. Treatment of these lesions and recurrent physician appointments can be a great inconvenience to patients, resulting in expenses to patients and loss of work and family time. The Mohs surgery technique is associated with a low recurrence rate for BCC and is preferred for higher risk tumors and for tumors in cosmetically sensitive sites on the head and neck. While recurrence rates of BCC post Mohs are 1-2% for primary basal cells, recent data is not available to validate this historical assessment. Currently, comprehensive rates of recurrence are not available because a national registry of recurrence rates for BCC and squamous cell carcinoma (SCC) does not exist. The purpose of this study is to both historically and prospectively assess current basal cell carcinoma recurrence rates in patients undergoing Mohs micrographic surgery.

Official TitleBasal Cell Carcinoma Recurrence
Principal SponsorNorthwestern University
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

115 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Cohort

These studies follow a group of individuals with common characteristics (such as a condition or birth year) over a specific period to study health outcomes or exposures.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Over 18 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

CarcinomaCarcinoma, Basal CellNeoplasmsNeoplasms by Histologic TypeNeoplasms by SiteNeoplasms, Glandular and EpithelialSkin DiseasesSkin NeoplasmsSkin and Connective Tissue DiseasesNeoplasms, Basal Cell

Criteria

4 inclusion criteria required to participate
Subjects with BCC lesions on the head, neck, genitalia, hands, or feet

Subjects who have undergone Mohs micrographic surgery for BCC on or before December 31, 2006

Subjects with a medical record at the respective site

Subjects in a stable health condition, as determined by the principle investigator

5 exclusion criteria prevent from participating
Subjects with basal cell nevus syndrome

Subjects with lesions only in areas other than the head, neck, genitalia,

hands and feet

Subjects who have not followed up through the Department of Dermatology

Show More Criteria

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Study Objectives

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 2 locations

Suspended

Northwestern University Feinberg School of Medicine, Department of Dermatology

Chicago, United StatesOpen Northwestern University Feinberg School of Medicine, Department of Dermatology in Google Maps
Suspended

DuPage Medical Group Dermatology

Naperville, United States
Completed2 Study Centers