Completed
The Effect of Intracameral Triesence (Triamcinolone Acetonide Injectable Suspension) on Ocular Inflammation After Trabeculectomy, Tube Shunt Implantation or Combined Trabeculectomy With Cataract Surgery
What is being tested
Triesence
+ balanced salt solution BSS
Drug
Who is being recruted
Eye Diseases+6
+ Glaucoma
+ Glaucoma, Open-Angle
Over 21 Years
+11 Eligibility Criteria
How is the trial designed
Treatment Study
Phase 2 & 3
Interventional
Study Start: February 2009
Summary
Principal SponsorWills Eye
Last updated: January 27, 2026
Sourced from a government-validated database.Claim as a partner
Study start date: February 1, 2009
Actual date on which the first participant was enrolled.Determine the efficacy and safety of intracameral Triesence in patients who undergo trabeculectomy, tube shunt, or combined cataract extraction, intra-ocular lens implantation and trabeculectomy with or without adjunctive mitomycin-C.
Official TitleThe Effect of Intracameral Triesence (Triamcinolone Acetonide Injectable Suspension) on Ocular Inflammation After Trabeculectomy, Tube Shunt Implantation or Combined Trabeculectomy With Cataract Surgery
Principal SponsorWills Eye
Last updated: January 27, 2026
Sourced from a government-validated database.Claim as a partner
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.Design Details
77 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Treatment Study
These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Conditions
Criteria
Any sex
Biological sex of participants that are eligible to enroll.Over 21 Years
Range of ages for which participants are eligible to join.Healthy volunteers not allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Eye DiseasesGlaucomaGlaucoma, Open-AngleIris DiseasesOcular HypertensionUveal DiseasesGlaucoma, NeovascularGlaucoma, Angle-ClosureExfoliation Syndrome
Criteria
7 inclusion criteria required to participate
glaucoma patients requiring surgery (Trabeculectomy or Express Shunt; Trabeculectomy plus Phacoemulsification and Interocular Lens Implant; Baerveldt Tube; Ahmed Tube; Molteno Tube)
primary open angle glaucoma
primary angle-closure glaucoma
pseudoexfoliation glaucoma
Show More Criteria
4 exclusion criteria prevent from participating
patients that are pregnant, nursing, or not using adequate contraception
any other eye surgery except cataract surgery
an infection, inflammation, or any abnormality preventing measurement of eye pressure
enrolled in another investigational study
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.Treatment Groups
Study Objectives
2 intervention groups are designated in this study
This study does not include a placebo group
Treatment Groups
Group I
Experimentalglaucoma surgery with 0.2cc Triesence adjunct.
Group II
Active Comparatorglaucoma surgery with balanced salt solution, the standard technique.
Study Objectives
Primary Objectives
Secondary Objectives
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 1 location
Suspended
CompletedOne Study Center