Completed

Comparison of Seasonal Allergic Rhinitis Treatment With 2 Antihistamines Used in Combination With Intranasal Corticosteroid

What is being tested

Olopatadine HCl Nasal Spray, 0.6%

+ Azelastine HCl Nasal Spray, 0.1%

Drug

Who is being recruted

Rhinitis, Allergic, Seasonal+9

+ Hypersensitivity

+ Hypersensitivity, Immediate

Over 12 Years

+13 Eligibility Criteria

See all eligibility criteria

How is the trial designed

Treatment Study

Phase 4

Interventional

Study Start: March 2009

See protocol details

Summary

Principal SponsorAlcon Research

Last updated: January 27, 2026

Sourced from a government-validated database.Claim as a partner

Study start date: March 1, 2009

Actual date on which the first participant was enrolled.

The purpose of this study is to compare the efficacy of Olopatadine Nasal Spray with Azelastine Nasal Spray when treatments are utilized in conjunction with Fluticasone Nasal Spray for the treatment of seasonal allergic rhinitis.

Official TitleComparison of Seasonal Allergic Rhinitis Treatment With 2 Antihistamines Used in Combination With Intranasal Corticosteroid

NCT00845195

Principal SponsorAlcon Research

Last updated: January 27, 2026

Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.

Design Details

150 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.

Conditions

Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Over 12 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Rhinitis, Allergic, SeasonalHypersensitivityHypersensitivity, ImmediateImmune System DiseasesInfectionsNose DiseasesOtorhinolaryngologic DiseasesRespiratory HypersensitivityRespiratory Tract DiseasesRespiratory Tract InfectionsRhinitisRhinitis, Allergic

Criteria

6 inclusion criteria required to participate

Able to provide consent/assent

History of spring/summer allergic rhinitis

Positive skin prick and/or intradermal test

Absence of significant anatomic abnormalities, infection, bleeding, and mucosal ulcerations

Show More Criteria

7 exclusion criteria prevent from participating

Asthma

Smoker

Concurrent disease such as rhinitis medicamentosa or large obstructive nasal polyps

History of current chronic sinusitis

Show More Criteria

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.

Treatment Groups

Study Objectives

2 intervention groups are designated in this study

This study does not include a placebo group

Treatment Groups

Group I

Experimental

Group II

Active Comparator

Study Objectives

Primary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

Alcon Call Center for Trial Locations

Fort Worth, United StatesOpen Alcon Call Center for Trial Locations in Google Maps

CompletedOne Study Center