Completed

Fluorine-18-α-Methyltyrosine Positron Emission Tomography to Measure Therapy

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What is being collected

Data Collection

Collected from today forward - Prospective
Who is being recruted

Bronchial Neoplasms+7

+ Carcinoma, Bronchogenic

+ Carcinoma, Non-Small-Cell Lung

Over 20 Years
+2 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Observational
See protocol details

Summary

Principal SponsorGunma University
Last updated: January 27, 2026
Sourced from a government-validated database.Claim as a partner

L-\[3-18F\]-α-methyltyrosine (18F-FMT) is an amino-acid tracer for positron emission tomography (PET). The investigators evaluated the value of 18F-FMT PET for the assessment of therapy response in patients with lung cancer as compared with that of 2-\[18F\]-fluoro-2-deoxy-D-glucose (18F-FDG) PET. The patients with lung cancer underwent PET studies with 18F-FDG and 18F-FMT before and after radio-/chemotherapy. The investigators used the ratio of the SUVmax of the mediastinal (N2) lymph node to the SUVmax of the primary tumor (N/P ratio ). All patients were divided into two groups of N/P ratio<1 and N/P ratio≥1, and the survival time was estimated by Kaplan-Meier method.

Official TitleFluorine-18-α-Methyltyrosine Positron Emission Tomography to Measure Therapy
NCT00826033
Principal SponsorGunma University
Last updated: January 27, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Over 20 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Bronchial NeoplasmsCarcinoma, BronchogenicCarcinoma, Non-Small-Cell LungLung DiseasesLung NeoplasmsNeoplasmsNeoplasms by SiteRespiratory Tract DiseasesRespiratory Tract NeoplasmsThoracic Neoplasms

Criteria

1 inclusion criteria required to participate
primary lung cancer All patients received first-line chemotherapy

1 exclusion criteria prevent from participating
Patients with diabetus mellitus

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

Gunma University Graduate School of Medicine

Gunma, JapanOpen Gunma University Graduate School of Medicine in Google Maps
CompletedOne Study Center