Suspended
Periodontal Disease and Cardiovascular Disease
What is being tested
Triclosan
+ Fluoride
Drug
Who is being recruted
Stomatognathic Diseases
+ Mouth Diseases
+ Periodontal Diseases
From 18 to 75 Years
+8 Eligibility Criteria
How is the trial designed
Treatment Study
Placebo-ControlledPhase 3
Interventional
Study Start: November 2000
Summary
Principal SponsorColgate Palmolive
Last updated: January 27, 2026
Sourced from a government-validated database.Claim as a partner
Study start date: November 1, 2000
Actual date on which the first participant was enrolled.To access the influence of triclosan dentifrice on the progression of periodontal disease in patients with coronary heart disease.
Official TitlePeriodontal Disease and Cardiovascular Disease
Principal SponsorColgate Palmolive
Last updated: January 27, 2026
Sourced from a government-validated database.Claim as a partner
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.Design Details
438 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Treatment Study
These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Conditions
Criteria
Any sex
Biological sex of participants that are eligible to enroll.From 18 to 75 Years
Range of ages for which participants are eligible to join.Healthy volunteers allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Stomatognathic DiseasesMouth DiseasesPeriodontal Diseases
Criteria
3 inclusion criteria required to participate
A minimum of 12 uncrowned teeth other than 3rd molars
Age 18 to 75 years
Informed consent
5 exclusion criteria prevent from participating
Prosthetic heart valves
Prosthetic joint replacement
Previous infective endocarditis
Requirement for antibiotic cover for dental treatment
Show More Criteria
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.Treatment Groups
Study Objectives
2 intervention groups are designated in this study
50% chance of being blinded to the placebo group
Treatment Groups
Group I
Active ComparatorGroup II
PlaceboStudy Objectives
Primary Objectives
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 1 location
Suspended
SuspendedOne Study Center