Completed
CIN2Management of Cervical Intraepithelial Neoplasia Grade 2
What is being tested
Excision of the lesion
+ Follow-up for spontaneous regression of the lesion
ProcedureOther
Who is being recruted
Urogenital Diseases+7
+ Genital Diseases
+ Uterine Cervical Diseases
From 18 to 61 Years
+2 Eligibility Criteria
How is the trial designed
Treatment Study
Phase 4
Interventional
Study Start: March 2003
Summary
Principal SponsorUniversidade Cidade de Sao Paulo
Last updated: January 27, 2026
Sourced from a government-validated database.Claim as a partner
Study start date: March 1, 2003
Actual date on which the first participant was enrolled.Pap smear and colposcopy were performed at every follow-up visit and all lesions were completely visible at colposcopy. The researchers purpose was to make some comments about the over treatment and the misclassification of CIN 2.
Official TitleManagement of Cervical Intraepithelial Neoplasia Grade 2
Principal SponsorUniversidade Cidade de Sao Paulo
Last updated: January 27, 2026
Sourced from a government-validated database.Claim as a partner
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.Design Details
90 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Treatment Study
These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Conditions
Criteria
Female
Biological sex of participants that are eligible to enroll.From 18 to 61 Years
Range of ages for which participants are eligible to join.Healthy volunteers not allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Urogenital DiseasesGenital DiseasesUterine Cervical DiseasesUterine Cervical DysplasiaFemale Urogenital Diseases and Pregnancy ComplicationsGenital Diseases, FemaleNeoplasmsPrecancerous ConditionsUterine DiseasesFemale Urogenital Diseases
Criteria
1 inclusion criteria required to participate
Histological CIN2 diagnosis
1 exclusion criteria prevent from participating
Previous CIN treatment
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.Treatment Groups
Study Objectives
2 intervention groups are designated in this study
This study does not include a placebo group
Treatment Groups
Group I
Active ComparatorGroup II
No InterventionStudy Objectives
Primary Objectives
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 1 location
Suspended
Leonor Mendes de Barros Maternity Hospital
São Paulo, BrazilOpen Leonor Mendes de Barros Maternity Hospital in Google MapsCompletedOne Study Center