Completed

Effect of Agaricus Blazei (Murrill) ss. Heinemann (Sun Mushroom) on the Nutritional State and Liver Biochemistry in Hepatitis C Patients.

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What is being tested

Agaricus blazei (Murrill) ss. Heinemann (sun mushroom)

Dietary Supplement
Who is being recruted

Blood-Borne Infections+8

+ Communicable Diseases

+ Digestive System Diseases

From 24 to 70 Years
+18 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Treatment Study

Interventional
Study Start: March 2003
See protocol details

Summary

Principal SponsorUPECLIN HC FM Botucatu Unesp
Last updated: January 27, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: March 1, 2003

Actual date on which the first participant was enrolled.

Ten patients were studied (5 - GI - not taking A. blazei - and 5 - G2 - taking A. blazei), from both sexes, with positive Anti-VHC and a healthy nutritional state, admitted into in the viral hepatitis ward. Diagnosis and treatment for hepatitis C concurred with the regulations of the Ministry of Health and nutritional evaluation was performed in 3 moments according to anthropometrical, bioimpedance, biochemical and dietary standards, with duration of 6 months. The consumption of A. blazei (10g/day) in dehydrated powder was concomitant with antiviral therapy (conventional or pegylated interferon associated with ribavirin) with duration of 5 months.

Official TitleEffect of Agaricus Blazei (Murrill) ss. Heinemann (Sun Mushroom) on the Nutritional State and Liver Biochemistry in Hepatitis C Patients.
NCT00564811
Principal SponsorUPECLIN HC FM Botucatu Unesp
Last updated: January 27, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

10 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 24 to 70 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Blood-Borne InfectionsCommunicable DiseasesDigestive System DiseasesHepatitisHepatitis, Viral, HumanHepatitis CInfectionsLiver DiseasesRNA Virus InfectionsVirus DiseasesFlaviviridae Infections

Criteria

9 inclusion criteria required to participate
To have been informed and signed adequately the free and clarified assent
Initiating the anti-viral treatment (interferon or pegylated interferon associate the ribavirin)
Age: 24-70 years
Gender :both the gender
Show More Criteria
9 exclusion criteria prevent from participating
Don't agree to the project or don't have signed the term of clarified free assent
Restriction for oral ingestion
The existence of surface of antigen of the hepatitis B virus(Ag HBs)
The existence of antibody for the human immunodeficiency virus
Show More Criteria

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

One single intervention group is designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Experimental

Study Objectives

Primary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

Internal Medicine Department, Botucatu School of Medicine, São Paulo State University - UNESP

Botucatu, BrazilOpen Internal Medicine Department, Botucatu School of Medicine, São Paulo State University - UNESP in Google Maps
CompletedOne Study Center