Suspended

Prevalence of Endometrial Abnormalities In Obese Women

0 criteria met from your profileSee at a glance how your profile meets each eligibility criteria.
What is being collected

Data Collection

Collected from today forward - Prospective
DNA Samples
Who is being recruted

Urogenital Diseases+17

+ Genital Diseases

+ Body Weight

From 30 to 55 Years
+17 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Case-Only

Examining characteristics of individuals with a disease in order to identify genetic or environmental factors contributing to the condition.
Observational
Study Start: June 2004
See protocol details

Summary

Principal SponsorM.D. Anderson Cancer Center
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: June 1, 2004

Actual date on which the first participant was enrolled.

Women in this study will be asked to complete three different parts of the study. All three parts of the study will be done during one visit to the gynecology center. First, you will be asked to complete a survey/questionnaire that will give researchers information on your background, weight history, gynecologic, and medical history. You will be assisted by a research nurse and completion of the questionnaire is expected take about 30 minutes. Second, you will be asked to have a blood sample drawn. About 2 tablespoons of blood will be drawn. This blood will be used to look at different hormone levels that may be related to your risk of endometrial abnormalities. Third, an endometrial biopsy will be performed by one of the doctors running the study. This will require you to have a full pelvic exam (much like when you have a pap smear), which will include looking at the cervix (mouth of the womb) and putting a small pipelle (straw) into the womb to collect a tissue sample. This procedure is routinely done in the office. You will not be required to take medications prior to the procedure and you will not receive a prescription for pain medication once the procedure is complete. Completion of all three parts of the study may take between one to two hours. You and your physician will be notified of your endometrial biopsy results. This is an investigational study. Up to 200 participants will be enrolled in this study. All will be enrolled at MD Anderson.

Official TitlePrevalence of Endometrial Abnormalities In Obese Women
NCT00500591
Principal SponsorM.D. Anderson Cancer Center
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

200 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Case-only

These studies focus only on individuals who have a specific disease. Researchers examine patterns—often genetic or environmental—to uncover what might be linked to the condition.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Female

Biological sex of participants that are eligible to enroll.

From 30 to 55 Years

Range of ages for which participants are eligible to join.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Urogenital DiseasesGenital DiseasesBody WeightFemale Urogenital Diseases and Pregnancy ComplicationsGenital Diseases, FemaleGenital Neoplasms, FemaleNeoplasmsNeoplasms by SiteNutrition DisordersNutritional and Metabolic DiseasesObesitySigns and SymptomsPathological Conditions, Signs and SymptomsUrogenital NeoplasmsUterine DiseasesUterine NeoplasmsEndometrial NeoplasmsOvernutritionOverweightFemale Urogenital Diseases

Criteria

6 inclusion criteria required to participate
Patients must have a measured BMI greater than or equal to 30 kg/m2 (obese) or less than or equal to 25 kg/m2 (lean) at the time of enrollment.
Patients must be between the ages of 30 and 55 years old at the time of enrollment.
Patients must not have taken any birth control (including pills, patch, injectables) for at least three months prior to enrollment.
Patients may not be pregnant at the time of enrollment (defined by negative urine pregnancy test).
Show More Criteria
11 exclusion criteria prevent from participating
Patients who have had a prior hysterectomy.
Patients who are pregnant or have a positive pregnancy test.
Patients with a prior history of endometrial hyperplasia or endometrial cancer.
Patients who are currently on birth control (including pills, patch, or injectable birth control).
Show More Criteria

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Study Objectives

Study Objectives

Primary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

University of Texas MD Anderson Cancer Center

Houston, United StatesOpen University of Texas MD Anderson Cancer Center in Google Maps
SuspendedOne Study Center