Completed
Experience of C4d Staining in Renal Allograft Biopsies
What is being collected
Data Collection
Collected from today forward - ProspectiveWho is being recruted
Over 18 Years
+2 Eligibility Criteria
How is the trial designed
Cohort
Tracking disease incidence in order to identify risk factors and understand disease progression over time.Observational
Study Start: July 2006
Summary
Principal SponsorHospital Authority, Hong Kong
Last updated: January 27, 2026
Sourced from a government-validated database.Claim as a partner
Study start date: July 1, 2006
Actual date on which the first participant was enrolled.Patients who had received kidney transplantation may suffer from rejection. Recently, positive staining for C4d in kidney biopsies of malfunctioning transplant kidney is increasingly recognized as an important prognostic indicator of poorer long-term kidney outcome. Data is, however, lacking in Hong Kong.
Official TitleExperience of C4d Staining in Renal Allograft Biopsies
Principal SponsorHospital Authority, Hong Kong
Last updated: January 27, 2026
Sourced from a government-validated database.Claim as a partner
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.Design Details
52 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Cohort
These studies follow a group of individuals with common characteristics (such as a condition or birth year) over a specific period to study health outcomes or exposures.
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Criteria
Any sex
Biological sex of participants that are eligible to enroll.Over 18 Years
Range of ages for which participants are eligible to join.Criteria
1 inclusion criteria required to participate
All renal allograft biopsies performed in Princess Margaret Hospital (PMH) during the period 1st April 2003 to 31st August 2005 for unexplained acute renal dysfunction (Creatinine rise from baseline by ≥ 20%) or delayed graft function in the immediate post-transplantation period were included in the study. Both cadaveric and living-donor transplant allografts were included.
1 exclusion criteria prevent from participating
patients who were < 18 years' old at the time of renal biopsy or whose records were so incomplete that preclude meaningful analysis
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 1 location
Suspended
CompletedOne Study Center