Completed

The Effect of Hyoscine Butyl Bromide on the First Stage of Labor in Term Pregnancies

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What is being tested

Data Collection

Who is being recruted

Over 18 Years
+5 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Treatment Study

Phase 2
Interventional
Study Start: June 2005
See protocol details

Summary

Principal SponsorUniversity Hospital of the West Indies
Last updated: January 27, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: June 1, 2005

Actual date on which the first participant was enrolled.

This study focuses on the effects of a medication called Hyoscine Butyl Bromide, or Buscopan®, during the first stage of labor in term pregnancies. The aim is to understand if this drug can safely speed up the process of cervical effacement and dilatation, potentially shortening the labor duration. This research is important as it could provide a new option for managing labor, potentially benefiting pregnant individuals and their babies. The study also investigates whether the use of Hyoscine Butyl Bromide during labor increases any risks, such as blood loss, the need for Caesarean deliveries, or lower neonatal APGAR scores. The study is designed as a double-blind, randomized, controlled clinical trial. This means that participants are randomly assigned to one of two groups, with one group receiving Hyoscine Butyl Bromide and the other group receiving a placebo (a harmless substance like normal saline that has no effect). Neither the participants nor the researchers know who is receiving the medication or the placebo. The study measures the effectiveness of Hyoscine Butyl Bromide by observing changes in cervical effacement and dilatation, and the overall duration of the first stage of labor. It also monitors for any potential complications to ensure the safety of both the mother and the baby.

Official TitleThe Effect of Hyoscine Butyl Bromide on the First Stage of Labor in Term Pregnancies
NCT00409890
Principal SponsorUniversity Hospital of the West Indies
Last updated: January 27, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

120 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.


Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Criteria

Female

Biological sex of participants that are eligible to enroll.

Over 18 Years

Range of ages for which participants are eligible to join.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Criteria

3 inclusion criteria required to participate
18 years of age or older

Term pregnancy

In spontaneous, established labour

2 exclusion criteria prevent from participating
Contraindication to vaginal delivery

Any chronic medical or pregnancy induced illness

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Study Objectives

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

University of the West Indies

Kingston, JamaicaOpen University of the West Indies in Google Maps
CompletedOne Study Center