Suspended
Magnesium Sulfate Versus Indomethacin for Preterm Labor
What is being tested
Data Collection
Who is being recruted
Urogenital Diseases+2
+ Female Urogenital Diseases and Pregnancy Complications
+ Obstetric Labor Complications
+16 Eligibility Criteria
How is the trial designed
Prevention Study
Phase 4
Interventional
Study Start: February 2003
Summary
Principal SponsorUniversity of Pennsylvania
Last updated: January 27, 2026
Sourced from a government-validated database.Claim as a partner
Study start date: February 1, 2003
Actual date on which the first participant was enrolled.The purpose of this study is to investigate the efficacy of Indomethacin compared to Magnesium Sulfate (MgSO4) in reducing neonatal morbidity through a prospective double blind randomized clinical trial. The specific aim of the project is to test the hypothesis that Indomethacin, compared to MgSO4, will decrease the proportion of neonates diagnosed with major complications or death.
Official TitleMagnesium Sulfate Versus Indomethacin for Preterm Labor
Principal SponsorUniversity of Pennsylvania
Last updated: January 27, 2026
Sourced from a government-validated database.Claim as a partner
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.Prevention Study
Prevention studies aim to stop a disease from developing. They often involve people at risk and test things like vaccines, lifestyle changes, or preventive medications.
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Conditions
Criteria
Female
Biological sex of participants that are eligible to enroll.Healthy volunteers allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsObstetric Labor ComplicationsObstetric Labor, PrematurePregnancy Complications
Criteria
5 inclusion criteria required to participate
Initial episode of preterm labor for enrollment
The diagnosis of preterm labor
Gestational age between 24 and 32 weeks
Singleton or twin gestation
Show More Criteria
11 exclusion criteria prevent from participating
Cervical dilation >5 cms
Suspected chorioamnionitis
Fetal distress
Vaginal bleeding
Show More Criteria
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 1 location
Suspended
SuspendedOne Study Center