Completed
A Multicenter Study to Assess the Cholesterol Lowering Level of Switching to an Investigational Drug Compared to Doubling the Dose of an Investigational Drug in Patients With Hypercholesterolemia and Atherosclerotic or Coronary Vascular Disease
What is being tested
Data Collection
Who is being recruted
Cardiovascular Diseases+7
+ Coronary Disease
+ Heart Diseases
Over 18 Years
How is the trial designed
Treatment Study
Phase 3
Interventional
Study Start: January 2004
Summary
Principal SponsorOrganon and Co
Last updated: December 11, 2025
Sourced from a government-validated database.Claim as a partner
Study start date: January 27, 2004
Actual date on which the first participant was enrolled.A 6-week treatment study to compare the reduction in cholesterol of two drugs MK0653A+Simvastatin for high cholesterol, in patients with hypercholesterolemia and atherosclerotic or coronary vascular disease.
Principal SponsorOrganon and Co
Last updated: December 11, 2025
Sourced from a government-validated database.Claim as a partner
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.Design Details
435 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Treatment Study
These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Conditions
Criteria
Any sex
Biological sex of participants that are eligible to enroll.Over 18 Years
Range of ages for which participants are eligible to join.Healthy volunteers not allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Cardiovascular DiseasesCoronary DiseaseHeart DiseasesHypercholesterolemiaHyperlipidemiasMetabolic DiseasesVascular DiseasesMyocardial IschemiaDyslipidemiasLipid Metabolism Disorders
Criteria
- Men and women greater than or equal to 18 years of age with elevated cholesterol levels and coronary heart disease (CHD), or atherosclerotic vascular disease may be eligible to participate in this study.
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.Study Objectives
Study Objectives
Primary Objectives
Secondary Objectives
CompletedNo study centers