Suspended

Assessment of Interactions Between IV Methamphetamine and Aripiprazole

0 criteria met from your profileSee at a glance how your profile meets each eligibility criteria.
What is being tested

Data Collection

Who is being recruted

Mental Disorders+1

+ Substance-Related Disorders

+ Amphetamine-Related Disorders

From 18 to 45 Years
See all eligibility criteria
How is the trial designed

Treatment Study

Phase 1
Interventional
Study Start: June 2004
See protocol details

Summary

Principal SponsorNational Institute on Drug Abuse (NIDA)
Last updated: December 11, 2025
Sourced from a government-validated database.Claim as a partner

Study start date: June 1, 2004

Actual date on which the first participant was enrolled.

This is a double-blind, placebo-controlled human laboratory clinical pharmacology study to assess potential interactions between intravenous d-methamphetamine infusion and treatment with oral aripiprazole.

Official TitleAssessment of Interactions Between IV Methamphetamine and Aripiprazole 
NCT00089440
Principal SponsorNational Institute on Drug Abuse (NIDA)
Last updated: December 11, 2025
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

17 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 18 to 45 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Mental DisordersSubstance-Related DisordersAmphetamine-Related DisordersChemically-Induced Disorders

Criteria

Inclusion Criteria: * Must meet DSM-4 criteria for methamphetamine abuse or dependence and are non-treatment seeking. * Ability to verbalize understanding of the consent form, able to provide written informed consent, and verbalize willingness to complete study procedures. Exclusion Criteria: * Please contact the site for more information.

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Study Objectives

Study Objectives

Primary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 2 locations

Suspended

UCLA Integrated Substance Abuse Program

Los Angeles, United StatesSee the location
Suspended

New York University, School of Medicine

New York, United States
Suspended2 Study Centers