Completed

Cranberry Juice Metabolites in Urine

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What is being tested

Data Collection

Who is being recruted

Urogenital Diseases+4

+ Female Urogenital Diseases and Pregnancy Complications

+ Infections

From 18 to 64 Years
See all eligibility criteria
How is the trial designed

Diagnostic Study

Interventional
Study Start: November 2000
See protocol details

Summary

Principal SponsorNational Center for Complementary and Integrative Health (NCCIH)
Last updated: January 14, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: November 1, 2000

Actual date on which the first participant was enrolled.

Urinary tract infections (UTIs) are a significant health issue, with one fourth of all women experiencing symptoms during their lifetimes. Cranberry juice has been shown to reduce the incidence of UTIs by preventing bacteria from adhering to the bladder. However, the compounds that direct this activity have not been identified. This study will identify and examine UTI-reducing compounds in cranberry juice. Participants in this study will drink a specified amount of water following an overnight fast. Their urine will be collected 1 to 3 hours after the water is consumed. Several days later, the women will be provided with cranberry juice to replace the water in the regimen. Urine samples will be analyzed for compounds that have antibacterial or antiadhesion activity against the bacteria that cause UTIs.

Official TitleCranberry Juice Metabolites in Urine 
NCT00087828
Principal SponsorNational Center for Complementary and Integrative Health (NCCIH)
Last updated: January 14, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

5 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Diagnostic Study

Diagnostic studies focus on improving how we detect or confirm a disease. They test new tools or techniques that could provide faster or more accurate diagnoses.


Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Female

Biological sex of participants that are eligible to enroll.

From 18 to 64 Years

Range of ages for which participants are eligible to join.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsInfectionsUrinary Tract InfectionsUrologic DiseasesFemale Urogenital DiseasesMale Urogenital Diseases

Criteria

Inclusion Criteria: * Good overall health Exclusion Criteria: * History of urinary tract infections * Use of cranberry products or antibiotics within 1 week of study start * Current use of any other medication * Hypertension * Diabetes * Pregnancy

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

Dept Medicinal Chemistry & Pharmacognosy, COP, UIC

Chicago, United StatesSee the location
CompletedOne Study Center