Cranberry Juice Impact on Antibiotic Absorption in UTI Treatment
Data Collection
Urogenital Diseases+4
+ Female Urogenital Diseases and Pregnancy Complications
+ Infections
Treatment Study
Summary
Study start date: July 1, 2006
Actual date on which the first participant was enrolled.Many people drink cranberry juice to prevent urinary tract infections (UTIs), even though its effectiveness is not fully proven. Recent findings suggest that cranberry juice might interfere with how the body processes antibiotics used for UTI treatment. This study aims to find out if drinking cranberry juice while taking two common UTI antibiotics, amoxicillin and cefaclor, reduces their concentration in the urine. The study involves children undergoing UTI treatment and adults without UTIs. Children participating in the study will continue their amoxicillin/cefaclor treatment as prescribed. After 7 to 10 days of antibiotic treatment, they will either receive cranberry juice for 2 days or no additional treatment. Urine samples will be taken from all child participants before and after giving cranberry juice to check antibiotic levels. Adult participants will receive two different doses of amoxicillin, either with or without cranberry juice. Blood and urine samples will be collected to see how cranberry juice affects the body's absorption and elimination of amoxicillin.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.18 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Treatment Study
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Any sex
Biological sex of participants that are eligible to enroll.From 6 to 50 Years
Range of ages for which participants are eligible to join.Healthy volunteers allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Criteria
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.Study Objectives
Primary Objectives
Secondary Objectives
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 1 location