Suspended

Rheopheresis Blood Filtration Study for the Treatment of Dry Age-Related Macular Degeneration (AMD)

0 criteria met from your profileSee at a glance how your profile meets each eligibility criteria.
What is being tested

Data Collection

Who is being recruted

Eye Diseases+1

+ Macular Degeneration

+ Retinal Degeneration

From 50 to 85 Years
See all eligibility criteria
How is the trial designed

Treatment Study

Phase 3
Interventional
Study Start: August 1999
See protocol details

Summary

Principal SponsorOccuLogix
Last updated: January 18, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: August 1, 1999

Actual date on which the first participant was enrolled.

AMD is a progressive disease of the retina which is nourished by a network of tiny blood vessels. There is evidence to suggest that the flow of nutrients to the retina is impaired in patients with AMD. Rheopheresis blood filtration uses blood filters that deplete excesses of large proteins, fats and other substances from the blood, improving blood flow to the macula, potentially improving vision.

Official TitleRheopheresis Blood Filtration Study for the Treatment of Dry Age-Related Macular Degeneration (AMD) 
NCT00078221
Principal SponsorOccuLogix
Last updated: January 18, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

180 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.


Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 50 to 85 Years

Range of ages for which participants are eligible to join.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Eye DiseasesMacular DegenerationRetinal DegenerationRetinal Diseases

Criteria

* Age 50-85 * Diagnosis of Dry AMD * BCVA between 20/32 and 20/125 in at least one eye * Numerous large plaques (soft drusen) * No history of HIV, Hepatitis B or C * Elevation of certain blood factors, such as total cholesterol, fibrinogen, and IgA

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 8 locations

Suspended

Retina Vitreous Associates

Beverly Hills, United StatesSee the location
Suspended

Aran Eye Associates

Coral Gables, United States
Suspended

Retina Health Care

Ft. Myers, United States
Suspended

UIC Eye Center

Chicago, United States
Suspended8 Study Centers