Completed

Suboxone: (Buprenorphine/Naloxone) Comparison of Two Taper Schedules

0 criteria met from your profileSee at a glance how your profile meets each eligibility criteria.
What is being tested

Data Collection

Who is being recruted

Narcotic-Related Disorders
+2

+ Mental Disorders
+ Opioid-Related Disorders
From 15 to 99 Years
See all eligibility criteria
How is the trial designed

Treatment Study

Phase 3
Interventional
Study Start: June 2003
See protocol details

Summary

Principal SponsorUniversity of California, Los Angeles
Last updated: January 14, 2026
Sourced from a government-validated database.Claim as a partner
Study start date: June 1, 2003Actual date on which the first participant was enrolled.

The purpose of this protocol is to to compare the clinical utility of two dosage tapering regimens in Buprenorphine/Naloxone stabilized subjects for opiate detoxification.

Official TitleSuboxone: (Buprenorphine/Naloxone) Comparison of Two Taper Schedules 
NCT00078117
Principal SponsorUniversity of California, Los Angeles
Last updated: January 14, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details
516 patients to be enrolledTotal number of participants that the clinical trial aims to recruit.
Treatment Study
These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria
Any sexBiological sex of participants that are eligible to enroll.
From 15 to 99 YearsRange of ages for which participants are eligible to join.
Healthy volunteers not allowedIf individuals who are healthy and do not have the condition being studied can participate.
Conditions
Pathology
Narcotic-Related Disorders
Mental Disorders
Opioid-Related Disorders
Substance-Related Disorders
Chemically-Induced Disorders
Criteria

Inclusion Criteria: * Females are not pregnant or lactating * Subjects meet DSM-IV criteria for opiate dependence, are medically and psychiatrically stable, and do not have a current history of benzodiazepine dependence abuse, dependence, or treatment

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Study Objectives
Study Objectives
Primary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.
This study has 11 locations
Suspended
Addiction Research & Treatment Services (ARTS)Denver, United StatesSee the location
Suspended
Denver Health & Hospitals AuthorityDenver, United States
Suspended
Hartford DispensaryHartford, United States
Suspended
Connecticut Counseling CentersWaterbury, United States
Completed11 Study Centers
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