Suspended

Medication Adherence in Older Psychotic People

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What is being tested

Data Collection

Who is being recruted

Mental Disorders+1

+ Psychotic Disorders

+ Schizophrenia

Over 40 Years
+3 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Interventional
Study Start: September 2002
See protocol details

Summary

Principal SponsorVeterans Medical Research Foundation
Last updated: January 27, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: September 1, 2002

Actual date on which the first participant was enrolled.

Psychoses are among the most common and serious psychiatric disorders. Currently, the most effective treatment for psychoses involves the use of antipsychotic or neuroleptic medications. Unfortunately, pharmacologic regimens often do not achieve their goals because of poor medication adherence. Nonadherence to antipsychotic treatment is a considerable public health problem that leads to myriad clinical and economic burdens, including psychotic relapse, increased clinic and emergency room visits, and rehospitalization. Participants in this study are randomly assigned to receive either MAT or supportive treatment for 12 weeks. MAT is given in 15 sessions and consists of motivational interviewing, education, and social skills and behavior modification. Individual MAT sessions are held in Weeks 1 and 12; small group sessions take place in Weeks 2 through 11. Three monthly booster group sessions begin in Week 16. Participants are assessed at baseline and at 3, 6, and 12 months. Medication adherence, psychopathology, quality of life, medication side effects, health beliefs, and functioning are assessed.

Official TitleMedication Adherence in Older Psychotic People
NCT00071604
Principal SponsorVeterans Medical Research Foundation
Last updated: January 27, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

240 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.


Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Over 40 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Mental DisordersPsychotic DisordersSchizophreniaSchizophrenia Spectrum and Other Psychotic Disorders

Criteria

3 inclusion criteria required to participate
DSM-IV criteria for schizophrenia or schizoaffective disorder

Outpatient status at the time of enrollment

Currently prescribed maintenance treatment with antipsychotic medication (typical or atypical, oral or depot)

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

Division of Geriatric Psychiatry Center (University of California, San Diego)

San Diego, United StatesOpen Division of Geriatric Psychiatry Center (University of California, San Diego) in Google Maps
SuspendedOne Study Center