Suspended

Cholesterol-Free Diet and Medication Impact in Cerebrotendinous Xanthomatosis (CTX)

0 criteria met from your profileSee at a glance how your profile meets each eligibility criteria.
What is being tested

chenodeoxycholic acid

+ lovastatin

Drug
Who is being recruted

Lipid Metabolism, Inborn Errors+10

+ Metabolic Diseases

+ Congenital, Hereditary, and Neonatal Diseases and Abnormalities

See all eligibility criteria
How is the trial designed

Treatment Study

Phase 2
Interventional
Study Start: January 1996
See protocol details

Summary

Principal SponsorNational Center for Research Resources (NCRR)
Study ContactSonja Connor
Last updated: June 24, 2005
Sourced from a government-validated database.Claim as a partner

Study start date: January 1, 1996

Actual date on which the first participant was enrolled.

PROTOCOL OUTLINE: Following a 2-week baseline assessment, patients participate in a feeding study for up to 3 weeks. The diet is free of cholesterol and cholestanol. For the next 4 weeks, patients return to their typical diet and are medicated with daily lovastatin and chenodeoxycholic acid. The feeding study is repeated for an additional 3 weeks, with the patient taking either lovastatin or chenodeoxycholic acid.

NCT00004346
Principal SponsorNational Center for Research Resources (NCRR)
Study ContactSonja Connor
Last updated: June 24, 2005
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

5 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Lipid Metabolism, Inborn ErrorsMetabolic DiseasesCongenital, Hereditary, and Neonatal Diseases and AbnormalitiesNutritional and Metabolic DiseasesPathologic ProcessesPathological Conditions, Signs and SymptomsXanthomatosisDisease AttributesGenetic Diseases, InbornLipid Metabolism DisordersMetabolism, Inborn ErrorsXanthomatosis, CerebrotendinousRare Diseases

Criteria

PROTOCOL ENTRY CRITERIA: Cerebrotendinous xanthomatosis

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Recruiting

Oregon Health and Science University

Portland, United StatesOpen Oregon Health and Science University in Google Maps
SuspendedOne Study Center