Completed

Pathogenic Mechanism of Spinocerebellar Ataxia Type 10 (SCA10)

0 criteria met from your profileSee at a glance how your profile meets each eligibility criteria.
What is being collected

Data Collection

Collected from today forward - Prospective
DNA Samples
Who is being recruted

Brain Diseases+14

+ Central Nervous System Diseases

+ Cerebellar Diseases

Over 3 Years
See all eligibility criteria
How is the trial designed

Cohort

Tracking disease incidence in order to identify risk factors and understand disease progression over time.
Observational
Study Start: November 1999
See protocol details

Summary

Principal SponsorOffice of Rare Diseases (ORD)
Last updated: March 6, 2012
Sourced from a government-validated database.Claim as a partner

Study start date: November 1, 1999

Actual date on which the first participant was enrolled.

PROTOCOL OUTLINE: Participants undergo a comprehensive clinical and molecular evaluation. Studies include: neurologic evaluation, including magnetic resonance imaging and nerve conduction studies; ophthalmologic exam; audiologic exam, including auditory brain stem evoked response; DNA extraction from blood, skin and muscle; genotype phenotype correlation. A neuropathologic evaluation is conducted postmortem, when possible.

NCT00004306
Principal SponsorOffice of Rare Diseases (ORD)
Last updated: March 6, 2012
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

18 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Cohort

These studies follow a group of individuals with common characteristics (such as a condition or birth year) over a specific period to study health outcomes or exposures.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Over 3 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Brain DiseasesCentral Nervous System DiseasesCerebellar DiseasesCongenital, Hereditary, and Neonatal Diseases and AbnormalitiesNervous System DiseasesPathologic ProcessesSigns and SymptomsSpinal Cord DiseasesPathological Conditions, Signs and SymptomsNeurodegenerative DiseasesHeredodegenerative Disorders, Nervous SystemDisease AttributesGenetic Diseases, InbornMental DisordersNeurologic ManifestationsSpinocerebellar DegenerationsRare Diseases

Criteria

Inclusion criteria: Subjects who have the diagnosis of SCA10 and their immediate relatives. Exclusion criteria: Children under 3 years of age, pregnant women, prisoners, mentally incapacitated subjects, and subjects who do not give consent.

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

University of Texas Medical Branch at Galveston

Galveston, United StatesOpen University of Texas Medical Branch at Galveston in Google Maps
CompletedOne Study Center
Pathogenic Mechanism of Spinocerebellar Ataxia Type 10 (SCA10) | PatLynk