Completed

Genetic Analysis of Complement-Related Proteins in IgA Glomerulonephritis Patients

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What is being collected

Data Collection

Who is being recruted

Autoimmune Diseases+12

+ Female Urogenital Diseases and Pregnancy Complications

+ Glomerulonephritis

See all eligibility criteria
How is the trial designed

Observational
Study Start: January 1998
See protocol details

Summary

Principal SponsorNational Center for Research Resources (NCRR)
Last updated: June 24, 2005
Sourced from a government-validated database.Claim as a partner

Study start date: January 1, 1998

Actual date on which the first participant was enrolled.

PROTOCOL OUTLINE: Participants undergo qualitative genetic analysis of complement-related proteins. Studies include: genomic re-arrangement of 4-gene unit, C4 DNA sequence and RNA expression, type-1 complement receptor DNA sequence, Fc-gamma receptor IIIA isoform analysis, classical and alternative complement activation pathway assays, plasma C4 and C4d protein levels, and immunoglobulin patterns in glomerular deposits.

NCT00004305
Principal SponsorNational Center for Research Resources (NCRR)
Last updated: June 24, 2005
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

105 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Autoimmune DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsGlomerulonephritisImmune System DiseasesKidney DiseasesNephritisPathologic ProcessesPathological Conditions, Signs and SymptomsUrologic DiseasesDisease AttributesFemale Urogenital DiseasesMale Urogenital DiseasesUrogenital DiseasesGlomerulonephritis, IGARare Diseases

Criteria

IgA glomerulonephritis

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Ohio State University

Columbus, United StatesOpen Ohio State University in Google Maps
CompletedOne Study Center