Completed

Comparison of Inhaled and Intravenous Pentamidine in PCP Treatment for AIDS Patients

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Study Aim

This study compares the effectiveness of inhaled and intravenous Pentamidine in treating Pneumocystis pneumonia (PCP) in patients living with AIDS.

What is being tested

Pentamidine isethionate

Drug
Who is being recruted

Blood-Borne Infections+28

+ Urogenital Diseases

+ Genital Diseases

Over 18 Years
+6 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Treatment Study

Interventional
See protocol details

Summary

Principal SponsorLyphoMed
Last updated: June 24, 2005
Sourced from a government-validated database.Claim as a partner

This study focuses on comparing two methods of delivering a medication called pentamidine in patients with AIDS who have Pneumocystis carinii pneumonia (PCP), a type of pneumonia. The goal is to determine which method works better. PCP is a common complication in AIDS patients, and finding the best way to treat it can significantly improve their quality of life and survival rates.

Principal SponsorLyphoMed
Last updated: June 24, 2005
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Over 18 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Blood-Borne InfectionsUrogenital DiseasesGenital DiseasesBacterial Infections and MycosesCommunicable DiseasesImmunologic Deficiency SyndromesImmune System DiseasesInfectionsLung DiseasesLung Diseases, FungalMycosesOpportunistic InfectionsPathologic ProcessesPneumoniaRespiration DisordersRespiratory Tract DiseasesRespiratory Tract InfectionsRetroviridae InfectionsRNA Virus InfectionsSexually Transmitted DiseasesSlow Virus DiseasesPathological Conditions, Signs and SymptomsVirus DiseasesSexually Transmitted Diseases, ViralLentivirus InfectionsPneumocystis InfectionsAcquired Immunodeficiency SyndromePneumonia, PneumocystisHIV InfectionsAIDS-Related Opportunistic InfectionsRespiratory Aspiration

Criteria

2 inclusion criteria required to participate
HIV antibody or AIDS and a clinical presentation suggesting PCP

Hospitalized at Cedars-Sinai Medical Center with AIDS and possible Pneumocystis carinii pneumonia (PCP)

4 exclusion criteria prevent from participating
History of asthma

Inability to understand the consent procedure

Previous history of adverse reaction to pentamidine

Pulmonary Kaposi's sarcoma

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

LyphoMed Inc

Rosemont, United StatesOpen LyphoMed Inc in Google Maps
CompletedOne Study Center