Completed

Platelet Function and Pharmacokinetics of AZT and Ibuprofen in HIV-Infected Hemophiliacs

0 criteria met from your profileSee at a glance how your profile meets each eligibility criteria.
What is being tested

Ibuprofen

+ Zidovudine

Drug
Who is being recruted

Blood-Borne Infections+20

+ Urogenital Diseases

+ Genital Diseases

Over 12 Years
+10 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Treatment Study

Interventional
See protocol details

Summary

Principal SponsorUniversity of Pittsburgh
Last updated: June 24, 2005
Sourced from a government-validated database.Claim as a partner

This study focuses on HIV-infected individuals who also have hemophilia, a condition that makes blood clotting difficult. The goal is to understand if taking two specific medications together, Azidothymidine (AZT) and Motrin (Ibuprofen), can lead to increased bleeding tendency. This research is important as it aims to ensure the safety and effectiveness of treatment plans for this unique patient population, potentially improving their care and quality of life.

NCT00002276
Principal SponsorUniversity of Pittsburgh
Last updated: June 24, 2005
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Over 12 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Blood-Borne InfectionsUrogenital DiseasesGenital DiseasesBlood Coagulation DisordersCommunicable DiseasesHematologic DiseasesHemic and Lymphatic DiseasesHemorrhagic DisordersImmunologic Deficiency SyndromesImmune System DiseasesInfectionsCongenital, Hereditary, and Neonatal Diseases and AbnormalitiesRetroviridae InfectionsRNA Virus InfectionsSexually Transmitted DiseasesVirus DiseasesSexually Transmitted Diseases, ViralLentivirus InfectionsCoagulation Protein DisordersBlood Coagulation Disorders, InheritedGenetic Diseases, InbornHemophilia AHIV Infections

Criteria

6 inclusion criteria required to participate
HIV-seropositivity confirmed by Western Blot
Patients must have Hemophilia
Not taking AZT
Required: Ibuprofen
Show More Criteria
4 exclusion criteria prevent from participating
Patients with hospitalization for opportunistic infection, bacterial infection or malignancy
Patients with hospitalization for opportunistic infection, bacterial infection, or malignancy as a prior condition
Excluded: AZT
Excluded: Antibiotics or other medication for opportunistic infection, bacterial infection, or malignancy

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Hemophilia Ctr of Western PA / Univ of Pittsburgh

Pittsburgh, United StatesOpen Hemophilia Ctr of Western PA / Univ of Pittsburgh in Google Maps
CompletedOne Study Center