Interferon Beta (Betaseron) Safety and Efficacy in AIDS and Advanced ARC Patients on Reduced-Dose AZT Regimen
Interferon beta-1b
+ Zidovudine
Blood-Borne Infections+14
+ Urogenital Diseases
+ Genital Diseases
Treatment Study
Summary
This is a study about the safety and efficacy of a drug called Betaseron, which is a type of interferon beta, in helping patients with AIDS and advanced AIDS related complex (ARC). These patients are also receiving a reduced dose of another drug called zidovudine, often referred to as AZT. The goal is to see if Betaseron can improve treatment for these patients, addressing the challenges faced in managing their condition. This research is important as it could potentially lead to better care for those affected by AIDS and ARC. The study is designed as a randomized, double-blind, placebo-controlled trial, meaning some participants will receive Betaseron while others will receive a placebo, and neither the participants nor the researchers will know who gets which. This helps ensure the results are unbiased. Participants will continue with their reduced-dose AZT regimen. The safety and effectiveness of Betaseron will be evaluated throughout the study, with careful monitoring for any potential side effects or benefits.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.Treatment Study
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Any sex
Biological sex of participants that are eligible to enroll.Over 18 Years
Range of ages for which participants are eligible to join.Healthy volunteers not allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Criteria
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 25 locations
USC School of Medicine / Norris Cancer Hosp
Los Angeles, United StatesCedars Sinai Med Ctr
Los Angeles, United StatesUCLA CARE Ctr
Los Angeles, United States