Completed
Delavirdine Mesylate, Zidovudine, and Indinavir Sulfate Treatment for HIV-1 Infected Individuals
What is being tested
Indinavir sulfate
+ Delavirdine mesylate
+ Zidovudine
Drug
Who is being recruted
Blood-Borne Infections+11
+ Urogenital Diseases
+ Genital Diseases
Over 14 Years
+6 Eligibility Criteria
How is the trial designed
Treatment Study
Interventional
Summary
Principal SponsorPharmacia and Upjohn
Last updated: June 24, 2005
Sourced from a government-validated database.Claim as a partner
Patients are divided into 2 treatment groups; the groups are balanced with respect to viral load. Group A receives ZDV, DLV, and IDV 3 times daily. Group B receives ZDV, DLV, and IDV 2 times daily. Patients are evaluated for changes from baseline in viral load and CD4 cell count.
Principal SponsorPharmacia and Upjohn
Last updated: June 24, 2005
Sourced from a government-validated database.Claim as a partner
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.Design Details
32 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Treatment Study
These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Conditions
Criteria
Any sex
Biological sex of participants that are eligible to enroll.Over 14 Years
Range of ages for which participants are eligible to join.Healthy volunteers not allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Blood-Borne InfectionsUrogenital DiseasesGenital DiseasesCommunicable DiseasesImmunologic Deficiency SyndromesImmune System DiseasesInfectionsRetroviridae InfectionsRNA Virus InfectionsSexually Transmitted DiseasesVirus DiseasesSexually Transmitted Diseases, ViralLentivirus InfectionsHIV Infections
Criteria
4 inclusion criteria required to participate
Are HIV-positive
Are at least 14 years old (consent of parent or guardian is required if under 18)
Have a CD4 cell count of at least 50 cells/mm3
Have a viral load (level of HIV in the blood) of at least 20,000 copies/ml
2 exclusion criteria prevent from participating
Have ever taken an anti-HIV drug other than ZDV
Have taken ZDV for more than 1 month
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 6 locations
UCSF AIDS Research Institute
San Francisco, United StatesSaint Luke's - Roosevelt Hosp Ctr
New York, United StatesAnderson Clinical Research
Pittsburgh, United StatesCompleted6 Study Centers