Completed
GENEVAX-HIV Vaccine Dose Escalation Study in HIV Seronegative Volunteers
What is being tested
APL 400-003
Biological
Who is being recruted
Blood-Borne Infections+11
+ Urogenital Diseases
+ Genital Diseases
From 18 to 60 Years
+14 Eligibility Criteria
How is the trial designed
Prevention Study
Phase 1
Interventional
Summary
Principal SponsorWyeth-Lederle Vaccines
Last updated: June 24, 2005
Sourced from a government-validated database.Claim as a partner
In this open-label study, volunteers are given an intramuscular injection of GENEVAX-HIV vaccine using the Biojector 2000. Safety measures and immune response are assessed accordingly.
Principal SponsorWyeth-Lederle Vaccines
Last updated: June 24, 2005
Sourced from a government-validated database.Claim as a partner
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.Prevention Study
Prevention studies aim to stop a disease from developing. They often involve people at risk and test things like vaccines, lifestyle changes, or preventive medications.
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Conditions
Criteria
Any sex
Biological sex of participants that are eligible to enroll.From 18 to 60 Years
Range of ages for which participants are eligible to join.Healthy volunteers allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Blood-Borne InfectionsUrogenital DiseasesGenital DiseasesCommunicable DiseasesImmunologic Deficiency SyndromesImmune System DiseasesInfectionsRetroviridae InfectionsRNA Virus InfectionsSexually Transmitted DiseasesVirus DiseasesSexually Transmitted Diseases, ViralLentivirus InfectionsHIV Infections
Criteria
4 inclusion criteria required to participate
Agree to use effective methods of birth control during the study
Are 18 - 60 years old
Are HIV-negative and in good health
Are able to understand how infections such as HIV are spread
10 exclusion criteria prevent from participating
Abuse alcohol or drugs or have an uncontrolled psychiatric disorder
Are allergic to bupivacaine, vaccines, or certain local anesthetics
Are pregnant or breast-feeding
Have an immune system disorder or have received therapy for an immune system disorder
Show More Criteria
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 1 location
Univ of Pennsylvania Med Ctr
Philadelphia, United StatesOpen Univ of Pennsylvania Med Ctr in Google MapsCompletedOne Study Center