Completed

Fluconazole vs Nystatin Oral Suspension for Oropharyngeal Candidiasis in AIDS Patients

0 criteria met from your profileSee at a glance how your profile meets each eligibility criteria.
What is being tested

Nystatin

+ Fluconazole

Drug
Who is being recruted

Blood-Borne Infections+20

+ Urogenital Diseases

+ Genital Diseases

Over 13 Years
+11 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Treatment Study

Interventional
See protocol details

Summary

Principal SponsorPfizer
Last updated: June 24, 2005
Sourced from a government-validated database.Claim as a partner

Patients are randomized to receive fluconazole oral suspension once daily (swallowed at approximately the same time every day) for 14 days or nystatin oral suspension used to rinse the mouth four times daily for 14 days. No food or drink is permitted immediately following the administration of the nystatin.

NCT00002112
Principal SponsorPfizer
Last updated: June 24, 2005
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Over 13 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Blood-Borne InfectionsUrogenital DiseasesGenital DiseasesBacterial Infections and MycosesCandidiasisCommunicable DiseasesImmunologic Deficiency SyndromesImmune System DiseasesInfectionsStomatognathic DiseasesMouth DiseasesMycosesRetroviridae InfectionsRNA Virus InfectionsSexually Transmitted DiseasesSlow Virus DiseasesVirus DiseasesSexually Transmitted Diseases, ViralLentivirus InfectionsAcquired Immunodeficiency SyndromeAIDS-Related ComplexCandidiasis, OralHIV Infections

Criteria

5 inclusion criteria required to participate
Allowed concurrent medications: Phenytoin, Oral hypoglycemics, Coumarin-type anticoagulants, Cyclosporine
Patients must have ARC or AIDS
Patients must have a life expectancy of at least 4 weeks
Patients must have confirmation of diagnosis by microscopic exam and culture of organism
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6 exclusion criteria prevent from participating
Excluded concurrent medications: Antifungal agents other than study drugs, Other experimental medications
Patients who are unable to tolerate oral medication
Patients who have taken other antifungal agents within the past 3 days
Patients with a known history of intolerance or allergy to imidazoles or triazoles or the polyene components of nystatin
Show More Criteria

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 5 locations

California Med Research Group

Fresno, United StatesOpen California Med Research Group in Google Maps

UCSF Hosp

San Francisco, United States

Johns Hopkins School of Medicine

Baltimore, United States

Med College of Pennsylvania

Philadelphia, United States
Completed5 Study Centers