Completed

Ditiocarb Sodium for Immune Function Restoration in AIDS and ARC Patients

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What is being tested

Ditiocarb sodium

Drug
Who is being recruted

Blood-Borne Infections+14

+ Urogenital Diseases

+ Genital Diseases

Over 18 Years
+6 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Treatment Study

Interventional
See protocol details

Summary

Principal SponsorMerieux Institute
Last updated: June 24, 2005
Sourced from a government-validated database.Claim as a partner

This study focuses on a drug called ditiocarb sodium, or DTC, and its potential benefits for patients diagnosed with AIDS and AIDS Related Complex (ARC). The main goal is to understand if DTC can help improve the immune system and overall health of these patients. The study also aims to find out if DTC can alleviate symptoms associated with ARC, slow down the progression from ARC to AIDS, or even delay the worsening of AIDS. Ultimately, the researchers hope to discover if DTC can extend the lifespan of individuals living with AIDS. During this treatment study, participants will receive DTC. The effects of DTC on the immune system and overall health will be carefully monitored. Researchers will observe if there are any improvements in ARC symptoms, and if the progression of the disease slows down. They will also track the survival rates of the participants to understand the potential long-term benefits of DTC. It's important to note that every medical study carries potential risks and benefits, which will be thoroughly explained to each participant before they decide to take part in the study.

Principal SponsorMerieux Institute
Last updated: June 24, 2005
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Over 18 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Blood-Borne InfectionsUrogenital DiseasesGenital DiseasesCommunicable DiseasesImmunologic Deficiency SyndromesImmune System DiseasesInfectionsRetroviridae InfectionsRNA Virus InfectionsSexually Transmitted DiseasesSlow Virus DiseasesVirus DiseasesSexually Transmitted Diseases, ViralLentivirus InfectionsAcquired Immunodeficiency SyndromeAIDS-Related ComplexHIV Infections

Criteria

2 inclusion criteria required to participate
Allowed concurrent medication: Zidovudine (AZT)

Patients must be either HIV seropositive or have AIDS or AIDS related complex (ARC) and have life expectancy of at least 6 months

4 exclusion criteria prevent from participating
Experimental AIDS therapy within 3 weeks of study entry

Patients with active opportunistic infection or progressive Kaposi's sarcoma (KS)

Patients with dementia

Patients with lymphoma

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 8 locations

Univ of Arizona / Arizona Cancer Ctr

Tucson, United StatesOpen Univ of Arizona / Arizona Cancer Ctr in Google Maps

USC School of Medicine / Norris Cancer Hosp

Los Angeles, United States

San Francisco AIDS Clinic / San Francisco Gen Hosp

San Francisco, United States

Portion Med Group

Sherman Oaks, United States
Completed8 Study Centers