Completed

Comparison of Ampicillin/Amoxicillin and Ceftriaxone for Salmonella Infections in AIDS Patients

0 criteria met from your profileSee at a glance how your profile meets each eligibility criteria.
What is being tested

Ceftriaxone sodium

+ Ampicillin sodium

+ Amoxicillin trihydrate

Drug
Who is being recruted

Blood-Borne Infections+20

+ Urogenital Diseases

+ Genital Diseases

Over 18 Years
+6 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Treatment Study

Interventional
See protocol details

Summary

Principal SponsorUniversity of Southern California
Last updated: June 24, 2005
Sourced from a government-validated database.Claim as a partner

This study focuses on comparing two different treatments for Salmonella infections in patients living with AIDS. The goal is to determine which treatment works better in managing these infections. Salmonella infections can be challenging to treat in individuals with AIDS, making this research particularly important for improving their care and quality of life. The two treatments being compared are a standard regimen using parenteral ampicillin and oral amoxicillin, and another regimen involving initial daily therapy with ceftriaxone, followed by a suppressive treatment given three times a week.

NCT00002052
Principal SponsorUniversity of Southern California
Last updated: June 24, 2005
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Over 18 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Blood-Borne InfectionsUrogenital DiseasesGenital DiseasesBacterial Infections and MycosesBacterial InfectionsCommunicable DiseasesEnterobacteriaceae InfectionsImmunologic Deficiency SyndromesImmune System DiseasesInfectionsOpportunistic InfectionsRetroviridae InfectionsRNA Virus InfectionsSexually Transmitted DiseasesSlow Virus DiseasesVirus DiseasesSexually Transmitted Diseases, ViralLentivirus InfectionsGram-Negative Bacterial InfectionsAcquired Immunodeficiency SyndromeSalmonella InfectionsHIV InfectionsAIDS-Related Opportunistic Infections

Criteria

6 exclusion criteria prevent from participating
HIV infection, AIDS, or AIDS related complex (ARC)
In a coma or with other central nervous system (CNS) impairment
Not expected to survive 12 weeks
Salmonella bacteremia or positive stool culture in patient with 3 or more stools per day
Show More Criteria

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Los Angeles County - USC Med Ctr

Los Angeles, United StatesOpen Los Angeles County - USC Med Ctr in Google Maps
CompletedOne Study Center