Completed

Low Dose Oral Interferon Alfa-n3 Treatment in ARC Patients

0 criteria met from your profileSee at a glance how your profile meets each eligibility criteria.
What is being tested

Interferon alfa-n3

Drug
Who is being recruted

Blood-Borne Infections+14

+ Urogenital Diseases

+ Genital Diseases

Over 18 Years
+19 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Treatment Study

Interventional
See protocol details

Summary

Principal SponsorInterferon Sciences
Last updated: June 24, 2005
Sourced from a government-validated database.Claim as a partner

The study has been extended to offer 52 weeks of maintenance therapy after the 10 weeks of the placebo controlled period are concluded successfully.

NCT00002012
Principal SponsorInterferon Sciences
Last updated: June 24, 2005
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

45 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Over 18 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Blood-Borne InfectionsUrogenital DiseasesGenital DiseasesCommunicable DiseasesImmunologic Deficiency SyndromesImmune System DiseasesInfectionsRetroviridae InfectionsRNA Virus InfectionsSexually Transmitted DiseasesSlow Virus DiseasesVirus DiseasesSexually Transmitted Diseases, ViralLentivirus InfectionsAcquired Immunodeficiency SyndromeAIDS-Related ComplexHIV Infections

Criteria

4 inclusion criteria required to participate
Allowed prior use of Zidovudine (AZT) at a dose = or < 600 mg/day at least 90 days prior to study entry

Been receiving a dose of = or < 600 mg/day of zidovudine (AZT) at least 90 days prior to study entry IF they are currently taking AZT

Diagnosis of AIDS related complex (ARC)

Given written informed consent

15 exclusion criteria prevent from participating
Absolute CD4 count of < 100 or > 350 cells/mm3

Active IV drug abuse within 3 months of study entry

Any disease or disorder listed in Patient Exclusion Co-existing Conditions

Development of antibodies to interferon during prior interferon therapy that occurred > 3 months prior to study entry

Show More Criteria

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Mount Sinai Med Ctr

New York, United StatesOpen Mount Sinai Med Ctr in Google Maps
CompletedOne Study Center