Completed

Clinical Manifestations of Mutations in Genes Linked to Familial Cardiomyopathy

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What is being collected

Data Collection

Who is being recruted

Aortic Valve Disease+12

+ Aortic Stenosis, Subvalvular

+ Aortic Valve Stenosis

See all eligibility criteria
How is the trial designed

Observational
Study Start: March 1999
See protocol details

Summary

Principal SponsorNational Heart, Lung, and Blood Institute (NHLBI)
Last updated: March 4, 2008
Sourced from a government-validated database.Claim as a partner

Study start date: March 1, 1999

Actual date on which the first participant was enrolled.

Familial cardiomyopathy (FC) often demonstrates both non-allelic and allelic genetic heterogeneity. We propose to determine the clinical correlates of specific genetic defects which cause FC by identifying and expanding a set of kindreds with identical and distinct molecular defects.

NCT00001881
Principal SponsorNational Heart, Lung, and Blood Institute (NHLBI)
Last updated: March 4, 2008
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

9999 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Aortic Valve DiseaseAortic Stenosis, SubvalvularAortic Valve StenosisCardiovascular DiseasesHeart DiseasesHeart Valve DiseasesHypertrophyCardiomyopathiesCongenital, Hereditary, and Neonatal Diseases and AbnormalitiesPathological Conditions, Signs and SymptomsPathological Conditions, AnatomicalGenetic Diseases, InbornCardiomyopathy, HypertrophicCardiomegalyCardiomyopathy, Hypertrophic, Familial

Criteria

Individuals with cardiomyopathy referred for evaluation to the NIH.

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

National Heart, Lung and Blood Institute (NHLBI)

Bethesda, United StatesOpen National Heart, Lung and Blood Institute (NHLBI) in Google Maps
CompletedOne Study Center