Evaluation of Cardiovascular Magnetic Resonance Imaging and Spectroscopy in Normal Volunteers
This study aims to observe and evaluate the heart's function and metabolism using cardiovascular magnetic resonance imaging and spectroscopy in healthy individuals.
Data Collection
Cardiovascular Diseases
Summary
Study start date: February 22, 1999
Actual date on which the first participant was enrolled.Technical evaluation of magnetic resonance imaging and spectroscopy will be performed on normal volunteers. These studies will be conducted in the NIH MRI systems located in Suburban Hospital in Bethesda, Maryland. These studies may involve the intravenous administration of commercially available MR contrast media and exercise. The results will be used to evaluate the performance of various pulse sequences, gradient coils, and RF coils on human subjects and will provide essential ground work for specific patient protocols.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.400 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Any sex
Biological sex of participants that are eligible to enroll.Over 18 Years
Range of ages for which participants are eligible to join.Healthy volunteers allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Criteria
INCLUSION CRITERIA: Any normal volunteer above the age 18 who is capable of giving informed consent will be included. EXCLUSION CRITERIA: A subject will be excluded if he/she has a contradiction to MR scanning. Brain aneurysm clip Implanted neural stimulator Implanted cardiac pacemaker implanted defibrillator Cochlear implant Ocular foreign body (e.g. metal shavings) Insulin pump Pregnant women (when uncertain, subjects will undergo urine or blood testing). Kidney Paralyzed hemidiaphragm Morbid obesity Claustrophobia Any condition in the PI's judgement which present unncessary risk EXCLUSION CRITERIA FOR GADOLINIUM ENHANCED STUDIES: Lactating women Subjects with hemoglobinopathies Asthma Renal or hepatic disease Subjects will be excluded if it is deemed that they have a condition that would preclude their use for technical development (e.g. paralyzed hemidiaphragm, morbid obesity, claustrophobia etc.) or present unnecessary risk (e.g. pregnancy, surgery of uncertain type, etc.). Lactating women and subjects with hemoglobinopathies, asthma, or renal or hepatic disease will be excluded from studies involving the adminstration of contrast agents.
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 1 location