Stimulation of the Human Central and Peripheral Nervous System With a Magnetic Stimulator
Data Collection
Central Nervous System Diseases+11
+ Metabolic Diseases
+ Metabolism, Inborn Errors
Summary
Study start date: February 1, 1998
Actual date on which the first participant was enrolled.This protocol outlines the use of magnetic stimulation as a diagnostic tool in patients with suspected dysfunction of central motor pathways or nerve roots and as a tool to localize and characterize suspected corticospinal abnormalities in neurologic disorders and systemic disorders with neurological manifestations. The protocol is intended for clinical use. Transcranial magnetic stimulation has been used for diagnosis of neurologic disorders since 1987. The principles of magnetic stimulation and its use for diagnosis are described in current textbooks of clinical neurophysiology as a routine procedure and should be included in the training program for fellows in clinical neurophysiology and electrodiagnostic medicine at NIH. The magnetic stimuli are to be given as single or paired pulses at repetition rates less than 1 per second.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.450 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Any sex
Biological sex of participants that are eligible to enroll.Healthy volunteers allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Criteria
INCLUSION CRITERIA: Adult patients with weakness or motor dysfunction. Children and adolescents with corticospinal tract signs. Normal volunteers, adults. Normal volunteers, children aged 4-17. EXCLUSION CRITERIA: Pregnant women. Subjects with implanted devices: pacemakers, medication pumps or defibrillators. Subjects with metal in the cranium except the mouth. Subjects with intracardiac lines. Normal subjects with history of seizures.
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 1 location
National Institute of Neurological Disorders and Stroke (NINDS)
Bethesda, United StatesOpen National Institute of Neurological Disorders and Stroke (NINDS) in Google Maps