Completed

Neurological Conditions Diagnosis and Natural History Study

Study Aim

This study aims to screen and evaluate patients with neurological conditions and their family members for potential enrollment in future research studies.

What is being collected

Data Collection

Collected from today forward - Prospective

Who is being recruted

Nervous System Diseases

From 2 to 100 Years

See all eligibility criteria

How is the trial designed

Other

Utilizing specific methods not covered by standard models in order to address unique research questions.

Observational

Study Start: September 1993

See protocol details

Summary

Principal SponsorNational Institute of Neurological Disorders and Stroke (NINDS)

Last updated: July 23, 2026

Sourced from a government-validated database.Claim as a partner

Study start date: September 30, 1993

Actual date on which the first participant was enrolled.

This protocol is a screening and natural history protocol, which allows for evaluation of patients and families where neurological conditions are present for enrollment into other studies and will also be used to screen healthy volunteers to create a pool of potential future HV matches for HMCS protocols. Through diagnostic evaluations, data will be collected for research use in this study.

NCT00001367

Principal SponsorNational Institute of Neurological Disorders and Stroke (NINDS)

Last updated: July 23, 2026

Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.

Design Details

3813 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Other

Some studies use unique or mixed approaches that don't fit standard categories. These may include innovative observational methods or studies tailored to specific research questions.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.

Conditions

Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 2 to 100 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Nervous System Diseases

Criteria

* INCLUSION CRITERIA: * Patients with neurological disorders and subjects with a family history of neurological conditions OR * Healthy volunteers: People age 18 or older who are generally in good health. EXCLUSION CRITERIA: * Patients \<2 years old. * Employees of HMCS in NINDS.

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.

Treatment Groups

Study Objectives

3 intervention groups are designated in this study

This study does not include a placebo group

Treatment Groups

Study Objectives

Primary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

National Institutes of Health Clinical Center

Bethesda, United StatesOpen National Institutes of Health Clinical Center in Google Maps

CompletedOne Study Center