Dextromethorphan for Neurodegenerative Disease Treatment
Data Collection
Synucleinopathies+6
+ Basal Ganglia Diseases
+ Brain Diseases
Treatment Study
Summary
Study start date: July 1, 1993
Actual date on which the first participant was enrolled.A study is underway to explore the potential of a drug called dextromethorphan in improving movement and thinking skills in individuals with neurodegenerative diseases, such as Alzheimer's or Parkinson's. The drug is believed to work by blocking certain receptors in the brain, which could help reduce symptoms. This research is crucial as it could pave the way for new treatments and improve the quality of life for those affected by these conditions.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.42 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Treatment Study
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Any sex
Biological sex of participants that are eligible to enroll.Healthy volunteers not allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Criteria
Parkinson's disease or other neurodegenerative disorders in which excessive stimulation of central glutamatergic pathways is hypothesized. Patients must be in good general health and have no history or clinical evidence of significant cardiac (including dysrhythmias), pulmonary, gastrointestinal, renal, hepatic, endocrine, hematological or psychiatric disease. Patient must not evidence any disorder which in the opinion of the investigator imposes an unnecessary risk to the patient or compromises the scientific interpretation of the data. Individuals of child bearing potential must practice appropriate methods of birth control.
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 1 location
National Institute of Neurological Disorders and Stroke (NINDS)
Bethesda, United StatesOpen National Institute of Neurological Disorders and Stroke (NINDS) in Google Maps