Completed

Lipoprotein Metabolism in Normal Volunteers and Dyslipoproteinemic Patients (Stable Isotopes)

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What is being collected

Data Collection

Who is being recruted

Hyperlipidemias
+2

+ Hyperlipoproteinemias
+ Metabolic Diseases
See all eligibility criteria
How is the trial designed

Observational
Study Start: December 1987
See protocol details

Summary

Principal SponsorNational Heart, Lung, and Blood Institute (NHLBI)
Last updated: January 18, 2026
Sourced from a government-validated database.Claim as a partner
Study start date: December 1, 1987Actual date on which the first participant was enrolled.

Apolipoproteins regulate the metabolism of lipids and lipoproteins in plasma of humans. In order to investigate the roles of apolipoproteins in these processes, we plan to quantitate the kinetics of the metabolism of apolipoproteins utilizing nonradioactive isotope labeled amino-acids.

Official TitleLipoprotein Metabolism in Normal Volunteers and Dyslipoproteinemic Patients (Stable Isotopes) 
NCT00001226
Principal SponsorNational Heart, Lung, and Blood Institute (NHLBI)
Last updated: January 18, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details
90 patients to be enrolledTotal number of participants that the clinical trial aims to recruit.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria
Any sexBiological sex of participants that are eligible to enroll.
Healthy volunteers allowedIf individuals who are healthy and do not have the condition being studied can participate.
Conditions
Pathology
Hyperlipidemias
Hyperlipoproteinemias
Metabolic Diseases
Dyslipidemias
Lipid Metabolism Disorders
Criteria

The subjects for these investigations will be either healthy normal volunteer control subjects or patients who have a dyslipoproteinemia. Subjects must be 18-80 years old.

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.
This study has 1 location
Suspended
National Heart, Lung and Blood Institute (NHLBI)Bethesda, United StatesSee the location
CompletedOne Study Center