Completed

Clinical Study of Oral Endosseous Titanium Implants in Edentulous Subjects

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What is being collected

Data Collection

Who is being recruted

Congenital Abnormalities+13

+ Abnormalities, Multiple

+ Jaw Diseases

See all eligibility criteria
How is the trial designed

Observational
Study Start: January 1986
See protocol details

Summary

Principal SponsorNational Institute of Dental and Craniofacial Research (NIDCR)
Last updated: March 4, 2008
Sourced from a government-validated database.Claim as a partner

Study start date: January 1, 1986

Actual date on which the first participant was enrolled.

The amendment to Clinical Protocol 86-D-0015, clinical study of Oral Endosseous Titanium Implants in Edentulous subjects, and patients with Ectodermal Dysplasia is to allow the Investigators to determine: (1) if placement of Endosseous Titanium Implants in pre-adolescent patients (age 7 to 10) will influence the growth and development of the craniomandibular complex. (2) The final position of the implant, the ability to fabricate prosthesis. (3) Body image, diet and perceived ease of chewing selected foods. Selection of patients for participation in the study will be based on the number of congenitally missing teeth associated with Ectodermal Dysplasia. At least 16 permanent teeth must be congenitally missing. A total of 30 patients will be included. A consent to participate in this study will be obtained from each patient: 18 & older - consent signed by patient 13-17 years - consent signed by parent, assent signed by patient 7-10 years - consent by parent, assent signed by child if capable of understanding or note on chart describing procedure used to obtain the child's assent to the study

NCT00001211
Principal SponsorNational Institute of Dental and Craniofacial Research (NIDCR)
Last updated: March 4, 2008
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

160 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Congenital AbnormalitiesAbnormalities, MultipleJaw DiseasesStomatognathic DiseasesMouth DiseasesMusculoskeletal DiseasesCongenital, Hereditary, and Neonatal Diseases and AbnormalitiesSkin AbnormalitiesSkin DiseasesSkin Diseases, GeneticTooth DiseasesSkin and Connective Tissue DiseasesGenetic Diseases, InbornEctodermal DysplasiaJaw, EdentulousMouth, Edentulous

Criteria

Individuals with a need for replacement maxillary and mandibular complete dentures.

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

National Institute of Dental And Craniofacial Research (NIDCR)

Bethesda, United StatesOpen National Institute of Dental And Craniofacial Research (NIDCR) in Google Maps
CompletedOne Study Center