Suspended

Brain Study of Patients With Frontal Lobe Dementia and Parkinsonian Disorders

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What is being collected

Data Collection

Who is being recruted

Alzheimer's Disease

+ Dementia

+ Down's Syndrome

Over 18 Years

See all eligibility criteria

How is the trial designed

Other

Observational

Study Start: January 1981

See protocol details

Summary

Principal SponsorNational Institute of Neurological Disorders and Stroke (NINDS)

Last updated: December 12, 2019

Sourced from a government-validated database.Claim as a partner

Study start date: January 19, 1981Actual date on which the first participant was enrolled.

The Cognitive Neuroscience Section of the National Institute of Neurological Disorders and Stroke proposes to continue its cross-sectional and longitudinal studies of cerebral metabolism in frontal lobe dementias and atypical basal ganglia disorders. These studies include repeated assessments of neuropsychological and brain anatomical and metabolic function in subjects with these important and possibly related brain disorders. Objective To continue the cross-sectional and longitudinal studies performed by the Cognitive Neuroscience Section of NINDS on the neuroanatomy, cerebral metabolism, neuropsychology, and genetics of frontotemporal dementia, corticobasal syndrome, and related brain disorders. Study population Frontal lobe dementias and atypical basal ganglia disorders including frontotemporal dementia, corticobasal syndrome, and related brain disorders. Design A cross-sectional assessment of neuropsychological, brain anatomical and metabolic function, and genetic measures in subjects with these disorders. Outcome measures MRI, FDG-PET, neuropsychological and clinical tests, genetics, and neuropathology.

Official TitleRegional Cerebral Utilization of Glucose in Patients With a Diagnosis of Frontal Lobe Dementia, Atypical Parkinsonian Disorder, and Other Basal Ganglia Disorders

Principal SponsorNational Institute of Neurological Disorders and Stroke (NINDS)

Last updated: December 12, 2019

Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.

Design Details

597 patients to be enrolledTotal number of participants that the clinical trial aims to recruit.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.

Conditions

Criteria

Any sexBiological sex of participants that are eligible to enroll.

Over 18 YearsRange of ages for which participants are eligible to join.

Healthy volunteers allowedIf individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Alzheimer's Disease

Dementia

Down's Syndrome

Criteria

No eligibility criteria are available at this time.Please check with the study contact for more details.

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Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

National Institutes of Health Clinical Center, 9000 Rockville PikeBethesda, United StatesSee the location

SuspendedOne Study Center