Zidovudine Triphosphate Levels in Maternal and Infant Cord Blood Cells
Data Collection
Blood-Borne Infections+11
+ Urogenital Diseases
+ Genital Diseases
Natural History
Observing the progression of a disease in untreated individuals in order to understand its typical course and outcomes.Summary
This study focuses on understanding how a drug called zidovudine triphosphate (AZT-TP) behaves inside the cells of pregnant women and their babies. The goal is to see how much of this drug is present in the blood cells of both mother and baby. This research is important because it can help doctors understand how well the drug is transferred from mother to baby during pregnancy, which could improve care for expectant mothers and their newborns. In this observational study, researchers will measure the levels of AZT-TP in the blood cells of both mothers and their babies. They will also compare these levels to the amounts of other natural substances in the cells. By doing so, they aim to understand how effectively the drug is transferred through the placenta, the organ that connects the mother and baby during pregnancy. This study does not involve any direct treatment or intervention, but rather observes and measures the drug's natural behavior in the body.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.24 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Natural History
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Female
Biological sex of participants that are eligible to enroll.Over 18 Years
Range of ages for which participants are eligible to join.Healthy volunteers not allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Criteria
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 6 locations
Univ of Medicine & Dentistry of New Jersey / Univ Hosp
Newark, United StatesOpen Univ of Medicine & Dentistry of New Jersey / Univ Hosp in Google MapsBellevue Hosp / New York Univ Med Ctr
New York, United StatesMount Sinai Med Ctr / Pediatrics
New York, United StatesRegional Med Ctr at Memphis
Memphis, United States