Completed

Zidovudine Triphosphate Levels in Maternal and Infant Cord Blood Cells

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What is being collected

Data Collection

Who is being recruted

Blood-Borne Infections+11

+ Urogenital Diseases

+ Genital Diseases

Over 18 Years
See all eligibility criteria
How is the trial designed

Natural History

Observing the progression of a disease in untreated individuals in order to understand its typical course and outcomes.
Observational
See protocol details

Summary

Principal SponsorNational Institute of Allergy and Infectious Diseases (NIAID)
Last updated: June 24, 2005
Sourced from a government-validated database.Claim as a partner

This study focuses on understanding how a drug called zidovudine triphosphate (AZT-TP) behaves inside the cells of pregnant women and their babies. The goal is to see how much of this drug is present in the blood cells of both mother and baby. This research is important because it can help doctors understand how well the drug is transferred from mother to baby during pregnancy, which could improve care for expectant mothers and their newborns. In this observational study, researchers will measure the levels of AZT-TP in the blood cells of both mothers and their babies. They will also compare these levels to the amounts of other natural substances in the cells. By doing so, they aim to understand how effectively the drug is transferred through the placenta, the organ that connects the mother and baby during pregnancy. This study does not involve any direct treatment or intervention, but rather observes and measures the drug's natural behavior in the body.

Principal SponsorNational Institute of Allergy and Infectious Diseases (NIAID)
Last updated: June 24, 2005
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

24 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Natural History

These studies observe how a disease progresses over time without active treatment. They help researchers understand how conditions typically develop, change, and impact quality of life.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions

Female

Biological sex of participants that are eligible to enroll.

Over 18 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Blood-Borne InfectionsUrogenital DiseasesGenital DiseasesCommunicable DiseasesImmunologic Deficiency SyndromesImmune System DiseasesInfectionsRetroviridae InfectionsRNA Virus InfectionsSexually Transmitted DiseasesVirus DiseasesSexually Transmitted Diseases, ViralLentivirus InfectionsHIV Infections

Criteria

No eligibility criteria are available at this time.Please check with the study contact for more details.

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 6 locations

Univ of Medicine & Dentistry of New Jersey / Univ Hosp

Newark, United StatesOpen Univ of Medicine & Dentistry of New Jersey / Univ Hosp in Google Maps

Bellevue Hosp / New York Univ Med Ctr

New York, United States

Mount Sinai Med Ctr / Pediatrics

New York, United States

Regional Med Ctr at Memphis

Memphis, United States
Completed6 Study Centers