Completed

Naltrexone for Alcohol Dependence Treatment in Diverse Settings

0 criteria met from your profileSee at a glance how your profile meets each eligibility criteria.
What is being tested

naltrexone (Revia)

+ Compliance Enhancement Tech.

+ Cognitive Behavior Therapy

DrugBehavioral
Who is being recruted

Mental Disorders+2

+ Substance-Related Disorders

+ Alcohol-Related Disorders

From 18 to 75 Years
+12 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Treatment Study

Phase 4
Interventional
See protocol details

Summary

Principal SponsorNational Institute on Alcohol Abuse and Alcoholism (NIAAA)
Last updated: June 24, 2005
Sourced from a government-validated database.Claim as a partner

This research program aims to discover more effective treatments for alcohol dependence. It combines medication, specifically Naltrexone (Revia), with suitable psychosocial support. The study focuses on individuals struggling with alcohol dependence and seeks to improve their care. The importance of this study lies in its potential to enhance treatment methods, addressing the challenges faced in managing alcohol dependence and meeting the unmet needs of those affected by this condition.

NCT00000452
Principal SponsorNational Institute on Alcohol Abuse and Alcoholism (NIAAA)
Last updated: June 24, 2005
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

240 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 18 to 75 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Mental DisordersSubstance-Related DisordersAlcohol-Related DisordersChemically-Induced DisordersAlcoholism

Criteria

5 inclusion criteria required to participate
Lives within a commutable distance to the Treatment Research Center and agrees to follow-up visits
Meets criteria for current diagnosis of alcohol dependence
Subjects used more than 15 standard alcohol drinks (average)/week with at least 1 day of 5 or more drinks in the past 30 days
Successful completion of medical detoxification
Show More Criteria
7 exclusion criteria prevent from participating
Current diagnosis of any substance dependence other than alcohol, nicotine, or marijuana
Current treatment with psychotropic medications, including disulfiram (Antabuse) (excluding short-term use of benzodiazepines for detoxification)
Evidence of opiate use in the past 30 days
Female subjects who are pregnant, nursing, or not using reliable method of contraception
Show More Criteria

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Treatment Research Center, University of Pennsylvania

Philadelphia, United StatesOpen Treatment Research Center, University of Pennsylvania in Google Maps
CompletedOne Study Center